Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LYPD6
  • Mouse genes Lypd6
  • Rat genes Lypd6
  • Zfish genes lypd6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lypd6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030550	acetylcholine receptor inhibitor activity	LYPD6	IDA		Human	PMID:27344019
Molecular Function	GO:0030550	acetylcholine receptor inhibitor activity	Lypd6	IDA		Rat	PMID:27344019|RGD:12050138
Molecular Function	GO:0030548	acetylcholine receptor regulator activity	Lypd6	IMP		Mouse	MGI:MGI:4430471|PMID:19403274
Molecular Function	GO:0005515	protein binding	LYPD6	IPI	UniProtKB:P17787	Human	PMID:27344019
Molecular Function	GO:0005515	protein binding	LYPD6	IPI	UniProtKB:P30532	Human	PMID:27344019
Molecular Function	GO:0005515	protein binding	LYPD6	IPI	UniProtKB:P30926	Human	PMID:27344019
Molecular Function	GO:0005515	protein binding	LYPD6	IPI	UniProtKB:P32297	Human	PMID:27344019
Molecular Function	GO:0005515	protein binding	LYPD6	IPI	UniProtKB:P36544	Human	PMID:27344019
Molecular Function	GO:0005515	protein binding	LYPD6	IPI	UniProtKB:P43681	Human	PMID:27344019
Molecular Function	GO:0005515	protein binding	LYPD6	IPI	UniProtKB:Q15825	Human	PMID:27344019
Molecular Function	GO:0005515	protein binding	LYPD6	IPI	UniProtKB:Q9UHA2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	lypd6	IPI	UniProtKB:O75581	Zfish	PMID:23987510|ZFIN:ZDB-PUB-130905-3
Molecular Function	GO:0005515	protein binding	lypd6	IPI	UniProtKB:O93274	Zfish	PMID:23987510|ZFIN:ZDB-PUB-130905-3
Cellular Component	GO:0016020	membrane	Lypd6	IDA		Rat	PMID:27344019|RGD:12050138
Cellular Component	GO:0043005	neuron projection	Lypd6	IDA		Rat	PMID:27344019|RGD:12050138
Cellular Component	GO:0005886	plasma membrane	lypd6	IDA		Zfish	PMID:23987510
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	lypd6	IGI	ZFIN:ZDB-GENE-980526-332	Zfish	PMID:23987510
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	lypd6	IGI	ZFIN:ZDB-GENO-090304-8,ZFIN:ZDB-MRPHLNO-131112-3	Zfish	PMID:23987510
Biological Process	GO:0060827	regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	lypd6	IMP	ZFIN:ZDB-MRPHLNO-131112-3	Zfish	PMID:23987510
Biological Process	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	lypd6	IMP	ZFIN:ZDB-MRPHLNO-131112-3	Zfish	PMID:23987510
Biological Process	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	lypd6	IGI	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-131112-3	Zfish	PMID:23987510
Biological Process	GO:0060061	Spemann organizer formation	lypd6	IGI	ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-131112-3	Zfish	PMID:23987510
Biological Process	GO:0060061	Spemann organizer formation	lypd6	IMP	ZFIN:ZDB-MRPHLNO-131112-3	Zfish	PMID:23987510

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern