Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LYPD1
  • Mouse genes Lypd1
  • Rat genes Lypd1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lypd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033130	acetylcholine receptor binding	Lypd1	IPI	PR:O70174	Mouse	PMID:19246390
Molecular Function	GO:0033130	acetylcholine receptor binding	Lypd1	IPI	PR:P49582	Mouse	PMID:19246390
Molecular Function	GO:0033130	acetylcholine receptor binding	Lypd1	IDA		Mouse	PMID:26276394
Molecular Function	GO:0030550	acetylcholine receptor inhibitor activity	Lypd1	IDA		Mouse	PMID:26276394
Molecular Function	GO:0030550	acetylcholine receptor inhibitor activity	Lypd1	IMP	MGI:MGI:3840549	Mouse	PMID:19246390
Molecular Function	GO:0005515	protein binding	Lypd1	IPI	UniProtKB:O70174	Mouse	MGI:MGI:5694852|PMID:26276394
Molecular Function	GO:0005515	protein binding	Lypd1	IPI	UniProtKB:O70174	Mouse	MGI:MGI:3838433|PMID:19246390
Cellular Component	GO:0016020	membrane	Lypd1	IDA		Mouse	PMID:19246390
Biological Process	GO:0095500	acetylcholine receptor signaling pathway	Lypd1	IDA		Mouse	PMID:26276394
Biological Process	GO:0001662	behavioral fear response	Lypd1	IMP	MGI:MGI:3840549	Mouse	PMID:19246390
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	Lypd1	IDA		Mouse	PMID:26276394
Biological Process	GO:0072659	protein localization to plasma membrane	Lypd1	IDA		Mouse	PMID:26276394
Biological Process	GO:0035094	response to nicotine	Lypd1	IMP	MGI:MGI:3840549	Mouse	PMID:19246390
Biological Process	GO:0007271	synaptic transmission, cholinergic	Lypd1	IDA		Mouse	PMID:19246390

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern