Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LSM14A
  • Mouse genes Lsm14a
  • Rat genes Lsm14a
  • Zfish genes lsm14aa,lsm14ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lsm14a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003690	double-stranded DNA binding	Lsm14a	IDA		Mouse	PMID:22745163
Molecular Function	GO:0003725	double-stranded RNA binding	Lsm14a	IDA		Mouse	PMID:22745163
Molecular Function	GO:0005515	protein binding	LSM14A	IPI	UniProtKB:P26196	Human	PMID:29510985
Molecular Function	GO:0005515	protein binding	LSM14A	IPI	UniProtKB:Q9NRA8	Human	PMID:29510985
Molecular Function	GO:0005515	protein binding	LSM14A	IPI	UniProtKB:P26196	Human	PMID:31422817
Molecular Function	GO:0005515	protein binding	LSM14A	IPI	UniProtKB:P26196	Human	PMID:31439631
Molecular Function	GO:0003723	RNA binding	LSM14A	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	LSM14A	HDA		Human	PMID:22681889
Molecular Function	GO:0003727	single-stranded RNA binding	Lsm14a	IDA		Mouse	PMID:22745163
Cellular Component	GO:0005737	cytoplasm	LSM14A	IDA		Human	PMID:16484376
Cellular Component	GO:0005737	cytoplasm	LSM14A	IDA		Human	PMID:17074753
Cellular Component	GO:0005737	cytoplasm	Lsm14a	IDA		Mouse	PMID:20014101
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	LSM14A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0010494	cytoplasmic stress granule	LSM14A	IDA		Human	PMID:16484376
Cellular Component	GO:0010494	cytoplasmic stress granule	LSM14A	IDA		Human	PMID:17074753
Cellular Component	GO:0005829	cytosol	LSM14A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0072686	mitotic spindle	LSM14A	IDA		Human	PMID:26339800
Cellular Component	GO:0000932	P-body	LSM14A	IDA		Human	PMID:16484376
Cellular Component	GO:0000932	P-body	LSM14A	IDA		Human	PMID:17074753
Cellular Component	GO:0000932	P-body	Lsm14a	IDA		Mouse	PMID:22745163
Biological Process	GO:0051607	defense response to virus	Lsm14a	IMP		Mouse	PMID:22745163
Biological Process	GO:0090307	mitotic spindle assembly	LSM14A	IMP		Human	PMID:26339800
Biological Process	GO:0017148	negative regulation of translation	LSM14A	IMP		Human	PMID:29510985
Biological Process	GO:0033962	P-body assembly	LSM14A	IDA		Human	PMID:16484376
Biological Process	GO:0033962	P-body assembly	LSM14A	IMP		Human	PMID:17074753
Biological Process	GO:0033962	P-body assembly	LSM14A	IMP		Human	PMID:29510985
Biological Process	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	Lsm14a	IDA		Mouse	PMID:22745163
Biological Process	GO:0039529	RIG-I signaling pathway	Lsm14a	IGI	MGI:MGI:2442858	Mouse	PMID:22745163
Biological Process	GO:0039529	RIG-I signaling pathway	Lsm14a	IGI	MGI:MGI:2444773	Mouse	PMID:22745163

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern