Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRRFIP2
  • Mouse genes Lrrfip2
  • Rat genes Lrrfip2
  • Zfish genes lrrfip2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrrfip2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030275	LRR domain binding	LRRFIP2	IPI	UniProtKB:Q13045	Human	PMID:10366446
Molecular Function	GO:0005515	protein binding	LRRFIP2	IPI	UniProtKB:Q92997	Human	PMID:15677333
Molecular Function	GO:0005515	protein binding	LRRFIP2	IPI	UniProtKB:Q8N5M1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	LRRFIP2	IPI	UniProtKB:Q8N5M1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Lrrfip2	IPI	PR:P22366	Mouse	PMID:19265123
Molecular Function	GO:0005515	protein binding	Lrrfip2	IPI	PR:Q9JJ28	Mouse	PMID:19265123
Biological Process	GO:0035660	MyD88-dependent toll-like receptor 4 signaling pathway	Lrrfip2	IDA		Mouse	PMID:19265123
Biological Process	GO:0002756	MyD88-independent toll-like receptor signaling pathway	Lrrfip2	IDA		Mouse	PMID:19265123
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Lrrfip2	IGI	MGI:MGI:108005	Mouse	PMID:19265123
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Lrrfip2	IGI	MGI:MGI:96824	Mouse	PMID:19265123
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Lrrfip2	IDA		Mouse	PMID:19265123
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Lrrfip2	IMP		Mouse	PMID:19265123
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Lrrfip2	IDA		Mouse	PMID:19265123

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern