Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LRFN5
  • Mouse genes Lrfn5
  • Rat genes Lrfn5
  • Zfish genes lrfn5a,lrfn5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lrfn5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	LRFN5	IPI	UniProtKB:Q92956	Human	PMID:27152329
Molecular Function	GO:0005515	protein binding	Lrfn5	IPI	UniProtKB:Q71F55	Mouse	MGI:MGI:6140757|PMID:27152329
Cellular Component	GO:0009986	cell surface	Lrfn5	IDA		Mouse	PMID:16828986
Cellular Component	GO:0098982	GABA-ergic synapse	Lrfn5	IDA		Mouse	PMID:20410109
Cellular Component	GO:0098982	GABA-ergic synapse	Lrfn5	IMP		Mouse	PMID:20410109
Cellular Component	GO:0098978	glutamatergic synapse	Lrfn5	IMP		Mouse	PMID:20410109
Cellular Component	GO:0098978	glutamatergic synapse	Lrfn5	IDA		Mouse	PMID:20410109
Cellular Component	GO:0098839	postsynaptic density membrane	Lrfn5	IDA		Rat	PMID:20410109|RGD:13702463
Biological Process	GO:0050728	negative regulation of inflammatory response	LRFN5	IDA		Human	PMID:27152329
Biological Process	GO:0043031	negative regulation of macrophage activation	Lrfn5	IMP		Mouse	MGI:MGI:6140757|PMID:27152329
Biological Process	GO:1905606	regulation of presynapse assembly	Lrfn5	IDA		Mouse	PMID:20410109
Biological Process	GO:1905606	regulation of presynapse assembly	Lrfn5	IMP		Mouse	PMID:20410109
Biological Process	GO:0099560	synaptic membrane adhesion	Lrfn5	EXP		Rat	PMID:27225731|RGD:13702436
Biological Process	GO:0099560	synaptic membrane adhesion	Lrfn5	IDA		Rat	PMID:27225731|RGD:13702436
Biological Process	GO:0099560	synaptic membrane adhesion	Lrfn5	IEP		Rat	PMID:27225731|RGD:13702436
Biological Process	GO:0099560	synaptic membrane adhesion	Lrfn5	IMP		Rat	PMID:27225731|RGD:13702436

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern