Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LDLRAD4
  • Mouse genes Ldlrad4
  • Rat genes Ldlrad4
  • Zfish genes ldlrad4a,ldlrad4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ldlrad4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070412	R-SMAD binding	LDLRAD4	IPI	UniProtKB:P84022	Human	PMID:24627487
Molecular Function	GO:0070412	R-SMAD binding	LDLRAD4	IPI	UniProtKB:Q15796	Human	PMID:24627487
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	LDLRAD4	IDA		Human	GO_REF:0000052
Biological Process	GO:0030336	negative regulation of cell migration	LDLRAD4	IMP		Human	PMID:24627487
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	LDLRAD4	IMP		Human	PMID:24627487
Biological Process	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	LDLRAD4	IMP		Human	PMID:24627487
Biological Process	GO:0010991	negative regulation of SMAD protein complex assembly	LDLRAD4	IDA		Human	PMID:24627487
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	LDLRAD4	IMP		Human	PMID:24627487
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Ldlrad4	IMP		Mouse	MGI:MGI:5583005|PMID:24627487

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern