Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LBX2
  • Mouse genes Lbx2
  • Rat genes Lbx2
  • Zfish genes lbx2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lbx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	lbx2	IPI	ZFIN:ZDB-GENE-990415-86	Zfish	PMID:25371059
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	LBX2	IDA		Human	PMID:28473536
Biological Process	GO:0000578	embryonic axis specification	lbx2	IMP		Zfish	PMID:25371059|ZFIN:ZDB-PUB-141106-9
Biological Process	GO:0055001	muscle cell development	lbx2	IMP	ZFIN:ZDB-MRPHLNO-100429-8	Zfish	PMID:19216761
Biological Process	GO:0055001	muscle cell development	lbx2	IMP	ZFIN:ZDB-MRPHLNO-100429-5	Zfish	PMID:19216761
Biological Process	GO:0042692	muscle cell differentiation	lbx2	IMP		Zfish	PMID:22406073|ZFIN:ZDB-PUB-120314-20
Biological Process	GO:1904105	positive regulation of convergent extension involved in gastrulation	lbx2	IMP		Zfish	PMID:22406073|ZFIN:ZDB-PUB-120314-20
Biological Process	GO:2000052	positive regulation of non-canonical Wnt signaling pathway	lbx2	IMP		Zfish	PMID:22406073|ZFIN:ZDB-PUB-120314-20
Biological Process	GO:0048922	posterior lateral line neuromast deposition	lbx2	IMP		Zfish	PMID:22216300|ZFIN:ZDB-PUB-120111-14
Biological Process	GO:0048920	posterior lateral line neuromast primordium migration	lbx2	IMP		Zfish	PMID:22216300|ZFIN:ZDB-PUB-120111-14
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	lbx2	IMP	ZFIN:ZDB-MRPHLNO-170915-3,ZFIN:ZDB-MRPHLNO-170915-4	Zfish	PMID:25371059
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	lbx2	IMP	ZFIN:ZDB-MRPHLNO-170915-2,ZFIN:ZDB-MRPHLNO-170919-3	Zfish	PMID:25371059

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern