Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes LANCL1
  • Mouse genes Lancl1
  • Rat genes Lancl1
  • Zfish genes lancl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Lancl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043295	glutathione binding	LANCL1	IDA		Human	PMID:19528316
Molecular Function	GO:0004364	glutathione transferase activity	Lancl1	IMP		Mouse	MGI:MGI:5604031|PMID:25158856
Molecular Function	GO:0050750	low-density lipoprotein particle receptor binding	LANCL1	IDA		Human	PMID:15082773
Molecular Function	GO:0005515	protein binding	LANCL1	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	LANCL1	IPI	UniProtKB:Q08509	Human	PMID:19528316
Molecular Function	GO:0005515	protein binding	LANCL1	IPI	UniProtKB:Q9UHR4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	LANCL1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0017124	SH3 domain binding	LANCL1	IPI	UniProtKB:Q08509	Human	PMID:19528316
Molecular Function	GO:0008270	zinc ion binding	LANCL1	IDA		Human	PMID:19528316
Biological Process	GO:0043523	regulation of neuron apoptotic process	Lancl1	IMP		Mouse	MGI:MGI:5604031|PMID:25158856
Biological Process	GO:1903203	regulation of oxidative stress-induced neuron death	Lancl1	IMP		Mouse	MGI:MGI:5604031|PMID:25158856

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern