Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KRT74
  • Mouse genes Krt74
  • Rat genes
  • Zfish genes krt4,krt5,zgc:158846
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Krt74

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990254	keratin filament binding	KRT74	IPI	UniProtKB:P02533	Human	PMID:20346438
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:O76014	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:O76015	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:P08727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:P08779	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:P13646	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:P19012	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:P61968	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:Q6A163	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:Q7Z3Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:Q7Z3Y9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:Q7Z3Z0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KRT74	IPI	UniProtKB:Q92764	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	KRT74	IDA		Human	PMID:20346438
Cellular Component	GO:0070062	extracellular exosome	KRT74	HDA		Human	PMID:23533145
Biological Process	GO:0031101	fin regeneration	krt5	IEP		Zfish	PMID:22278371
Biological Process	GO:0045104	intermediate filament cytoskeleton organization	KRT74	IDA		Human	PMID:20346438

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern