Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KLRC2,KLRC4
  • Mouse genes Klrc2
  • Rat genes Klrc2,Klrc3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klrc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0062081	activating MHC class Ib receptor activity	KLRC2	IDA		Human	PMID:9754572
Molecular Function	GO:0023024	MHC class I protein complex binding	KLRC2	IPI	UniProtKB:P13747	Human	PMID:18448674
Molecular Function	GO:1990405	protein antigen binding	KLRC2	IDA		Human	PMID:18448674
Molecular Function	GO:0005515	protein binding	KLRC2	IPI	UniProtKB:Q13241	Human	PMID:18083576
Molecular Function	GO:0005515	protein binding	KLRC2	IPI	UniProtKB:Q13241	Human	PMID:18448674
Molecular Function	GO:0005515	protein binding	KLRC2	IPI	UniProtKB:Q13241	Human	PMID:32575403
Molecular Function	GO:0005515	protein binding	KLRC2	IPI	UniProtKB:O43914	Human	PMID:9655483
Molecular Function	GO:0005515	protein binding	KLRC2	IPI	UniProtKB:Q13241	Human	PMID:9655483
Cellular Component	GO:0009897	external side of plasma membrane	Klrc2	IDA		Mouse	PMID:14707119
Cellular Component	GO:0005886	plasma membrane	KLRC2	IDA		Human	PMID:21825173
Cellular Component	GO:0005886	plasma membrane	KLRC2	IDA		Human	PMID:9655483
Cellular Component	GO:0043235	receptor complex	KLRC2	IDA		Human	PMID:18448674
Biological Process	GO:0002228	natural killer cell mediated immunity	KLRC2	IDA		Human	PMID:18448674
Biological Process	GO:0043323	positive regulation of natural killer cell degranulation	KLRC2	IDA		Human	PMID:21825173
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	KLRC2	IDA		Human	PMID:9754572
Biological Process	GO:0002223	stimulatory C-type lectin receptor signaling pathway	KLRC2	IDA		Human	PMID:9655483

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern