Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KIN
  • Mouse genes Kin
  • Rat genes Kin
  • Zfish genes kin
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kin

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003690	double-stranded DNA binding	Kin	IDA		Mouse	MGI:MGI:59940|PMID:1923796
Molecular Function	GO:0005515	protein binding	KIN	IPI	UniProtKB:Q9BUU2	Human	PMID:23349634
Molecular Function	GO:0003723	RNA binding	KIN	IDA		Human	PMID:17045609
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	KIN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016363	nuclear matrix	KIN	IDA		Human	PMID:12754299
Cellular Component	GO:0005654	nucleoplasm	KIN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Kin	IDA		Mouse	MGI:MGI:84658|PMID:8954809
Cellular Component	GO:0032991	protein-containing complex	KIN	IDA		Human	PMID:23349634
Biological Process	GO:0006974	DNA damage response	KIN	IEP		Human	PMID:12853634
Biological Process	GO:0006974	DNA damage response	Kin	IEP		Mouse	MGI:MGI:84658|PMID:8954809
Biological Process	GO:0006260	DNA replication	KIN	IDA		Human	PMID:12359749
Biological Process	GO:0006260	DNA replication	Kin	IDA		Mouse	MGI:MGI:84658|PMID:8954809

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern