Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNJ5
  • Mouse genes Kcnj5
  • Rat genes Kcnj5
  • Zfish genes kcnj5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnj5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005242	inward rectifier potassium channel activity	KCNJ5	IDA		Human	PMID:12297500
Molecular Function	GO:0005242	inward rectifier potassium channel activity	KCNJ5	IDA		Human	PMID:20560207
Molecular Function	GO:0005515	protein binding	KCNJ5	IPI	UniProtKB:P14416-1	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ5	IPI	UniProtKB:P21917	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ5	IPI	UniProtKB:P48051	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ5	IPI	UniProtKB:P48549	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ5	IPI	UniProtKB:Q92806	Human	PMID:12297500
Molecular Function	GO:0005515	protein binding	KCNJ5	IPI	UniProtKB:Q99712	Human	PMID:32296183
Molecular Function	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	KCNJ5	IMP		Human	PMID:20560207
Cellular Component	GO:0009897	external side of plasma membrane	Kcnj5	IDA		Rat	PMID:11561006|RGD:1581474
Cellular Component	GO:0030315	T-tubule	Kcnj5	IDA		Rat	PMID:11561006|RGD:1581474
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNJ5	IDA		Human	PMID:20560207
Biological Process	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential	KCNJ5	IMP		Human	PMID:20560207
Biological Process	GO:1990573	potassium ion import across plasma membrane	KCNJ5	IDA		Human	PMID:12297500
Biological Process	GO:1990573	potassium ion import across plasma membrane	KCNJ5	IDA		Human	PMID:20560207
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	KCNJ5	IMP		Human	PMID:20560207

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern