Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNJ12,KCNJ18
  • Mouse genes Kcnj12
  • Rat genes Kcnj12
  • Zfish genes kcnj12a,kcnj12b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnj12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005242	inward rectifier potassium channel activity	KCNJ18	IDA		Human	PMID:20074522
Molecular Function	GO:0005242	inward rectifier potassium channel activity	KCNJ18	IMP		Human	PMID:21665951
Molecular Function	GO:0005242	inward rectifier potassium channel activity	KCNJ12	IDA		Human	PMID:20921230
Molecular Function	GO:0005242	inward rectifier potassium channel activity	kcnj12b	IDA		Zfish	PMID:25991088
Molecular Function	GO:0005242	inward rectifier potassium channel activity	kcnj12a	IDA		Zfish	PMID:25991088
Molecular Function	GO:0030165	PDZ domain binding	Kcnj12	IPI	RGD:2505	Rat	PMID:11181181|RGD:1581466
Molecular Function	GO:0005515	protein binding	KCNJ18	IPI	UniProtKB:P50402	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ18	IPI	UniProtKB:P63252	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNJ18	IPI	UniProtKB:P63252	Human	PMID:32541000
Molecular Function	GO:0005515	protein binding	KCNJ12	IPI	UniProtKB:Q14160	Human	PMID:24550280
Molecular Function	GO:0005515	protein binding	KCNJ12	IPI	UniProtKB:Q14160	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	KCNJ12	IPI	UniProtKB:P50402	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:620730	Rat	PMID:14960569|RGD:1304295
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:1307068	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:1307728	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:1308648	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:1311833	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:1561985	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:1565768	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:2505	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:2507	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:619895	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:620014	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:620015	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:62004	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:620844	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:621164	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:621256	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:68423	Rat	PMID:15024025|RGD:1581350
Molecular Function	GO:0005515	protein binding	Kcnj12	IPI	RGD:68424	Rat	PMID:15024025|RGD:1581350
Cellular Component	GO:0030425	dendrite	Kcnj12	IDA		Rat	PMID:12591157|RGD:1581468
Cellular Component	GO:0016020	membrane	KCNJ12	IDA		Human	PMID:20921230
Cellular Component	GO:0043025	neuronal cell body	Kcnj12	IDA		Rat	PMID:12591157|RGD:1581468
Cellular Component	GO:0005886	plasma membrane	KCNJ18	IDA		Human	PMID:20074522
Cellular Component	GO:0005886	plasma membrane	KCNJ18	IDA		Human	PMID:21665951
Cellular Component	GO:0030315	T-tubule	Kcnj12	IDA		Rat	PMID:11181181|RGD:1581466
Biological Process	GO:0071805	potassium ion transmembrane transport	kcnj12a	IDA		Zfish	PMID:25991088|ZFIN:ZDB-PUB-150521-7
Biological Process	GO:0071805	potassium ion transmembrane transport	kcnj12b	IDA		Zfish	PMID:25991088|ZFIN:ZDB-PUB-150521-7
Biological Process	GO:0006813	potassium ion transport	KCNJ12	IDA		Human	PMID:20921230
Biological Process	GO:0051289	protein homotetramerization	KCNJ12	IDA		Human	PMID:21874019

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern