Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNJ1
  • Mouse genes Kcnj1
  • Rat genes Kcnj1
  • Zfish genes kcnj1a.1,kcnj1a.2,kcnj1a.3,kcnj1a.4,kcnj1a.5,kcnj1a.6,kcnj1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnj1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Kcnj1	IDA		Rat	PMID:11956191|RGD:14995323
Molecular Function	GO:0015272	ATP-activated inward rectifier potassium channel activity	Kcnj1	IDA		Rat	PMID:7611454|RGD:1581458
Molecular Function	GO:0005242	inward rectifier potassium channel activity	Kcnj1	IMP		Rat	PMID:16906771|RGD:1625250
Molecular Function	GO:0005242	inward rectifier potassium channel activity	Kcnj1	IMP		Rat	PMID:9015377|RGD:151356612
Molecular Function	GO:0005242	inward rectifier potassium channel activity	kcnj1a.1	IDA		Zfish	PMID:21262879
Molecular Function	GO:0042277	peptide binding	Kcnj1	IDA		Rat	PMID:16906771|RGD:1625250
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	KCNJ1	IDA		Human	PMID:12086641
Molecular Function	GO:0030955	potassium ion binding	Kcnj1	IMP		Rat	PMID:16906771|RGD:1625250
Cellular Component	GO:0005886	plasma membrane	Kcnj1	IDA		Rat	PMID:16906771|RGD:1625250
Biological Process	GO:0071286	cellular response to magnesium ion	Kcnj1	IDA		Rat	PMID:21030597|RGD:7244391
Biological Process	GO:0072359	circulatory system development	Kcnj1	IMP	MGI:MGI:2388372	Mouse	PMID:12122007
Biological Process	GO:0010467	gene expression	Kcnj1	IMP		Mouse	PMID:21081491
Biological Process	GO:0001822	kidney development	Kcnj1	IMP	MGI:MGI:2388372	Mouse	PMID:12122007
Biological Process	GO:0043066	negative regulation of apoptotic process	Kcnj1	IMP		Rat	PMID:22811560|RGD:7244389
Biological Process	GO:0009791	post-embryonic development	Kcnj1	IMP	MGI:MGI:2388372	Mouse	PMID:12122007
Biological Process	GO:1990573	potassium ion import across plasma membrane	Kcnj1	IMP		Rat	PMID:9015377|RGD:151356612
Biological Process	GO:0071805	potassium ion transmembrane transport	kcnj1a.1	IDA		Zfish	PMID:21262879|ZFIN:ZDB-PUB-110131-15
Biological Process	GO:0006813	potassium ion transport	Kcnj1	IDA		Rat	PMID:11567030|RGD:70578
Biological Process	GO:0006813	potassium ion transport	Kcnj1	IMP		Rat	PMID:16906771|RGD:1625250
Biological Process	GO:1900128	regulation of G-protein activated inward rectifier potassium channel activity	Kcnj1	IMP	MGI:MGI:2388372	Mouse	PMID:12130653
Biological Process	GO:0070294	renal sodium ion absorption	Kcnj1	IMP	MGI:MGI:2388372	Mouse	PMID:12122007
Biological Process	GO:0035864	response to potassium ion	Kcnj1	IEP		Rat	PMID:20702602|RGD:7244392
Biological Process	GO:0001894	tissue homeostasis	Kcnj1	IMP	MGI:MGI:2388372	Mouse	PMID:12122007

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern