Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes INPP4B
  • Mouse genes Inpp4b
  • Rat genes Inpp4b
  • Zfish genes inpp4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Inpp4b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008289	lipid binding	Inpp4b	IDA		Mouse	PMID:16631325
Molecular Function	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	Inpp4b	IDA		Mouse	PMID:21982707
Molecular Function	GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	Inpp4b	IDA		Mouse	PMID:21982707
Molecular Function	GO:0016316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity	Inpp4b	IDA		Rat	PMID:9295334|RGD:633135
Molecular Function	GO:0005515	protein binding	INPP4B	IPI	UniProtKB:Q9ULZ3	Human	PMID:24407287
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Inpp4b	IGI	MGI:MGI:1100089	Mouse	PMID:21982707
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	Inpp4b	IGI	MGI:MGI:1100089	Mouse	PMID:21982707
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	Inpp4b	IGI	MGI:MGI:102469	Mouse	PMID:21982707
Biological Process	GO:0045671	negative regulation of osteoclast differentiation	Inpp4b	IMP		Mouse	PMID:21982707
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	Inpp4b	IDA		Rat	PMID:9295334|RGD:633135
Biological Process	GO:0046850	regulation of bone remodeling	Inpp4b	IMP	MGI:MGI:5297505	Mouse	PMID:21982707
Biological Process	GO:0046822	regulation of nucleocytoplasmic transport	Inpp4b	IMP		Mouse	PMID:21982707
Biological Process	GO:0051896	regulation of protein kinase B signaling	Inpp4b	IMP		Mouse	PMID:23078915

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern