Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IGSF1
  • Mouse genes Igsf1
  • Rat genes Igsf1
  • Zfish genes si:dkey-23a13.11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Igsf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0038102	activin receptor antagonist activity	IGSF1	IDA		Human	PMID:11266516
Molecular Function	GO:0015026	coreceptor activity	Igsf1	IDA		Rat	PMID:11266515|RGD:633133
Molecular Function	GO:0034711	inhibin binding	IGSF1	IDA		Human	PMID:11266516
Molecular Function	GO:0005515	protein binding	IGSF1	IPI	UniProtKB:O00238	Human	PMID:11266516
Molecular Function	GO:0005515	protein binding	IGSF1	IPI	UniProtKB:P27037	Human	PMID:11266516
Molecular Function	GO:0005515	protein binding	IGSF1	IPI	UniProtKB:P36896	Human	PMID:11266516
Molecular Function	GO:0005515	protein binding	IGSF1	IPI	UniProtKB:P37023	Human	PMID:11266516
Molecular Function	GO:0005515	protein binding	IGSF1	IPI	UniProtKB:Q04771	Human	PMID:11266516
Molecular Function	GO:0005515	protein binding	IGSF1	IPI	UniProtKB:Q13705	Human	PMID:11266516
Molecular Function	GO:0005515	protein binding	IGSF1	IPI	UniProtKB:Q9ULT8	Human	PMID:12421765
Cellular Component	GO:0016020	membrane	IGSF1	IDA		Human	PMID:11266516
Biological Process	GO:0032926	negative regulation of activin receptor signaling pathway	IGSF1	IDA		Human	PMID:11266516
Biological Process	GO:0006355	regulation of DNA-templated transcription	IGSF1	IDA		Human	PMID:11266516

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern