Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HYPK
  • Mouse genes Hypk
  • Rat genes Hypk
  • Zfish genes hypk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hypk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HYPK	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	HYPK	IPI	UniProtKB:P42858	Human	PMID:17947297
Molecular Function	GO:0005515	protein binding	HYPK	IPI	UniProtKB:Q9BXJ9	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	HYPK	IPI	UniProtKB:P40222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HYPK	IPI	UniProtKB:P43355	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HYPK	IPI	UniProtKB:Q9BXJ9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	HYPK	IPI	UniProtKB:P40222	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HYPK	IPI	UniProtKB:Q2NKX9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HYPK	IPI	UniProtKB:Q9BXJ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HYPK	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Hypk	IPI	PR:P42859	Mouse	PMID:25446099
Molecular Function	GO:0044183	protein folding chaperone	HYPK	EXP		Human	PMID:18076027
Molecular Function	GO:0044183	protein folding chaperone	HYPK	IDA		Human	PMID:18076027
Cellular Component	GO:0005737	cytoplasm	HYPK	IDA		Human	PMID:17947297
Cellular Component	GO:0005737	cytoplasm	Hypk	IDA		Mouse	PMID:25446099
Cellular Component	GO:0015630	microtubule cytoskeleton	HYPK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HYPK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	HYPK	IDA		Human	PMID:17947297
Cellular Component	GO:0032991	protein-containing complex	HYPK	IDA		Human	PMID:17947297
Biological Process	GO:0043066	negative regulation of apoptotic process	HYPK	IDA		Human	PMID:17947297
Biological Process	GO:0050821	protein stabilization	HYPK	IDA		Human	PMID:17947297

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern