Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HSPE1
  • Mouse genes Hspe1-rs1
  • Rat genes Hspe1
  • Zfish genes hspe1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hspe1-rs1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008083	growth factor activity	Hspe1-rs1	IDA		Mouse	PMID:11210183
Molecular Function	GO:0005515	protein binding	HSPE1	IPI	UniProtKB:Q8WWX9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPE1	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HSPE1	IPI	UniProtKB:O00255	Human	PMID:9989505
Molecular Function	GO:0051087	protein-folding chaperone binding	HSPE1	IPI	UniProtKB:P10809	Human	PMID:10205158
Molecular Function	GO:0003723	RNA binding	HSPE1	HDA		Human	PMID:22658674
Cellular Component	GO:0070062	extracellular exosome	HSPE1	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	HSPE1	HDA		Human	PMID:16210410
Cellular Component	GO:0005759	mitochondrial matrix	Hspe1	IDA		Rat	PMID:7904573|RGD:729181
Cellular Component	GO:0005739	mitochondrion	HSPE1	IDA		Human	PMID:10205158
Cellular Component	GO:0005739	mitochondrion	Hspe1-rs1	HDA		Mouse	PMID:18614015
Biological Process	GO:0001649	osteoblast differentiation	HSPE1	HDA		Human	PMID:16210410

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern