Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HPS3
  • Mouse genes Hps3
  • Rat genes Hps3
  • Zfish genes hps3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hps3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HPS3	IPI	UniProtKB:Q86YV9	Human	PMID:25189619
Molecular Function	GO:0005515	protein binding	HPS3	IPI	UniProtKB:A0A0H3NFP4	Human	PMID:31611645
Molecular Function	GO:0005515	protein binding	hps3	IPI	ZFIN:ZDB-GENE-070410-80	Zfish	PMID:23893484
Cellular Component	GO:0031084	BLOC-2 complex	HPS3	IPI		Human	PMID:15030569
Cellular Component	GO:0031084	BLOC-2 complex	HPS3	IPI	UniProtKB:Q86YV9	Human	PMID:15030569
Cellular Component	GO:0031084	BLOC-2 complex	HPS3	IPI	UniProtKB:Q9UPZ3	Human	PMID:15030569
Cellular Component	GO:0005737	cytoplasm	Hps3	IDA		Mouse	PMID:11707070
Biological Process	GO:0006996	organelle organization	Hps3	IMP	MGI:MGI:1856707	Mouse	PMID:11707070
Biological Process	GO:0043473	pigmentation	Hps3	IMP	MGI:MGI:1856707	Mouse	PMID:2379821

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern