Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HLTF
  • Mouse genes Hltf
  • Rat genes Hltf
  • Zfish genes hltf
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hltf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	Hltf	IDA		Mouse	PMID:9427542
Molecular Function	GO:0005515	protein binding	HLTF	IPI	UniProtKB:Q02447	Human	PMID:10391891
Molecular Function	GO:0005515	protein binding	HLTF	IPI	UniProtKB:P12004	Human	PMID:18316726
Molecular Function	GO:0005515	protein binding	HLTF	IPI	UniProtKB:P61088	Human	PMID:18316726
Molecular Function	GO:0005515	protein binding	HLTF	IPI	UniProtKB:Q9NS91	Human	PMID:18316726
Molecular Function	GO:0005515	protein binding	HLTF	IPI	UniProtKB:P12004	Human	PMID:18719106
Molecular Function	GO:0005515	protein binding	HLTF	IPI	UniProtKB:P61088	Human	PMID:18719106
Molecular Function	GO:0005515	protein binding	HLTF	IPI	UniProtKB:Q9NS91	Human	PMID:18719106
Molecular Function	GO:0005515	protein binding	HLTF	IPI	UniProtKB:P60903	Human	PMID:23415230
Molecular Function	GO:0003723	RNA binding	HLTF	HDA		Human	PMID:22658674
Molecular Function	GO:0061630	ubiquitin protein ligase activity	HLTF	EXP		Human	PMID:18316726
Molecular Function	GO:0061630	ubiquitin protein ligase activity	HLTF	EXP		Human	PMID:18719106
Molecular Function	GO:0061630	ubiquitin protein ligase activity	HLTF	EXP		Human	PMID:19723507
Molecular Function	GO:0061630	ubiquitin protein ligase activity	HLTF	EXP		Human	PMID:21396873
Molecular Function	GO:0061630	ubiquitin protein ligase activity	HLTF	EXP		Human	PMID:26350214
Molecular Function	GO:0031625	ubiquitin protein ligase binding	HLTF	IDA		Human	PMID:25023518
Cellular Component	GO:0016020	membrane	HLTF	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	HLTF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	HLTF	EXP		Human	PMID:23415230
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	Hltf	IPI		Mouse	MGI:MGI:5469743|PMID:23415230
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	Hltf	IDA		Mouse	MGI:MGI:5469743|PMID:23415230
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hltf	IDA		Mouse	MGI:MGI:1100629|PMID:9427542
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Hltf	IDA		Mouse	MGI:MGI:5469743|PMID:23415230
Biological Process	GO:0050767	regulation of neurogenesis	Hltf	IDA		Mouse	MGI:MGI:5469743|PMID:23415230

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern