Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HEATR1
  • Mouse genes Heatr1
  • Rat genes Heatr1
  • Zfish genes heatr1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Heatr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	HEATR1	IPI	UniProtKB:Q76353	Human	PMID:22190034
Molecular Function	GO:0003723	RNA binding	HEATR1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	HEATR1	HDA		Human	PMID:22681889
Cellular Component	GO:0001650	fibrillar center	HEATR1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	HEATR1	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	HEATR1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	HEATR1	IDA		Human	PMID:17699751
Biological Process	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	heatr1	IMP	ZFIN:ZDB-GENO-060926-1	Zfish	PMID:16531401
Biological Process	GO:0043066	negative regulation of apoptotic process	heatr1	IMP	ZFIN:ZDB-GENO-060926-1	Zfish	PMID:16531401
Biological Process	GO:2000234	positive regulation of rRNA processing	HEATR1	IMP		Human	PMID:17699751
Biological Process	GO:0045943	positive regulation of transcription by RNA polymerase I	HEATR1	IMP		Human	PMID:17699751
Biological Process	GO:0043487	regulation of RNA stability	heatr1	IMP	ZFIN:ZDB-GENO-060926-1	Zfish	PMID:16531401

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern