Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HDAC10
  • Mouse genes Hdac10
  • Rat genes Hdac10
  • Zfish genes hdac10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hdac10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047611	acetylspermidine deacetylase activity	hdac10	IDA		Zfish	PMID:28516954
Molecular Function	GO:0019213	deacetylase activity	HDAC10	IDA		Human	PMID:28516954
Molecular Function	GO:0019899	enzyme binding	HDAC10	IPI	UniProtKB:O15379	Human	PMID:11861901
Molecular Function	GO:0004407	histone deacetylase activity	HDAC10	IDA		Human	PMID:11861901
Molecular Function	GO:0042826	histone deacetylase binding	HDAC10	IDA		Human	PMID:11861901
Molecular Function	GO:0005515	protein binding	HDAC10	IPI	UniProtKB:O43809	Human	PMID:17172643
Molecular Function	GO:0005515	protein binding	HDAC10	IPI	UniProtKB:P11142	Human	PMID:23801752
Molecular Function	GO:0005515	protein binding	HDAC10	IPI	UniProtKB:P43246	Human	PMID:26221039
Molecular Function	GO:0005515	protein binding	HDAC10	IPI	UniProtKB:Q9BYV2	Human	PMID:31391242
Molecular Function	GO:0005515	protein binding	HDAC10	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HDAC10	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HDAC10	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HDAC10	IPI	UniProtKB:P54252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HDAC10	IPI	UniProtKB:Q7Z412	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HDAC10	IPI	UniProtKB:Q92870-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	HDAC10	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0033558	protein lysine deacetylase activity	HDAC10	IDA		Human	PMID:17172643
Molecular Function	GO:0033558	protein lysine deacetylase activity	HDAC10	IDA		Human	PMID:26221039
Molecular Function	GO:0008270	zinc ion binding	hdac10	IDA		Zfish	PMID:28516954
Cellular Component	GO:0005737	cytoplasm	HDAC10	IDA		Human	PMID:11726666
Cellular Component	GO:0005737	cytoplasm	HDAC10	IDA		Human	PMID:11861901
Cellular Component	GO:0005829	cytosol	HDAC10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000118	histone deacetylase complex	HDAC10	IDA		Human	PMID:11861901
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	HDAC10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HDAC10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	HDAC10	IDA		Human	PMID:11726666
Cellular Component	GO:0005634	nucleus	HDAC10	IDA		Human	PMID:11861901
Biological Process	GO:0016575	histone deacetylation	HDAC10	IDA		Human	PMID:11861901
Biological Process	GO:0035825	homologous recombination	HDAC10	IMP		Human	PMID:21247901
Biological Process	GO:0016236	macroautophagy	HDAC10	IMP		Human	PMID:23801752
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	HDAC10	IDA		Human	PMID:11726666
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	HDAC10	IDA		Human	PMID:11861901
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	HDAC10	IDA		Human	PMID:11726666
Biological Process	GO:0014003	oligodendrocyte development	Hdac10	IEP		Rat	PMID:18627006|RGD:2306445
Biological Process	GO:0034983	peptidyl-lysine deacetylation	HDAC10	IDA		Human	PMID:26221039
Biological Process	GO:0106047	polyamine deacetylation	HDAC10	IDA		Human	PMID:28516954
Biological Process	GO:0106047	polyamine deacetylation	hdac10	IDA		Zfish	PMID:28516954
Biological Process	GO:0032425	positive regulation of mismatch repair	HDAC10	IDA		Human	PMID:26221039
Biological Process	GO:0006355	regulation of DNA-templated transcription	HDAC10	IDA		Human	PMID:11861901
Biological Process	GO:0106048	spermidine deacetylation	HDAC10	IDA		Human	PMID:28516954
Biological Process	GO:0106048	spermidine deacetylation	hdac10	IDA		Zfish	PMID:28516954

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern