Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes HACD2
  • Mouse genes Hacd2
  • Rat genes Hacd2
  • Zfish genes hacd2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hacd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0080023	(3R)-3-hydroxyacyl-CoA dehydratase activity	HACD2	EXP		Human	PMID:18554506
Molecular Function	GO:0019899	enzyme binding	HACD2	IDA		Human	PMID:18554506
Molecular Function	GO:0005515	protein binding	HACD2	IPI	UniProtKB:P51572	Human	PMID:15024066
Molecular Function	GO:0005515	protein binding	HACD2	IPI	UniProtKB:Q9NZ01	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	HACD2	IPI	UniProtKB:Q9NZ01	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	HACD2	IPI	UniProtKB:B2RUZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HACD2	IPI	UniProtKB:Q13651	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HACD2	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HACD2	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HACD2	IPI	UniProtKB:Q9NZ01	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	HACD2	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Molecular Function	GO:0102158	very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity	HACD2	IDA		Human	PMID:18554506
Cellular Component	GO:0005783	endoplasmic reticulum	HACD2	IDA		Human	PMID:15024066
Cellular Component	GO:0005783	endoplasmic reticulum	HACD2	IDA		Human	PMID:18554506
Biological Process	GO:0030497	fatty acid elongation	HACD2	IDA		Human	PMID:18554506
Biological Process	GO:0030148	sphingolipid biosynthetic process	HACD2	IGI	UniProtKB:P40857	Human	PMID:18554506
Biological Process	GO:0042761	very long-chain fatty acid biosynthetic process	HACD2	IDA		Human	PMID:18554506

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern