Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GTF2A2
  • Mouse genes Gtf2a2
  • Rat genes Gtf2a2
  • Zfish genes gtf2a2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gtf2a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GTF2A2	IPI	UniProtKB:P52655	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GTF2A2	IPI	UniProtKB:P52655	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GTF2A2	IPI	UniProtKB:P52655	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GTF2A2	IPI	UniProtKB:P52655	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GTF2A2	IPI	UniProtKB:Q9C029	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GTF2A2	IPI	UniProtKB:P20226	Human	PMID:7724559
Molecular Function	GO:0005515	protein binding	GTF2A2	IPI	UniProtKB:P20226	Human	PMID:8626665
Molecular Function	GO:0005515	protein binding	GTF2A2	IPI	UniProtKB:P52655	Human	PMID:8626665
Molecular Function	GO:0046982	protein heterodimerization activity	GTF2A2	IPI	UniProtKB:P52655	Human	PMID:8626665
Molecular Function	GO:0042803	protein homodimerization activity	GTF2A2	IPI	UniProtKB:P52657	Human	PMID:8626665
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	GTF2A2	IDA		Human	PMID:27193682
Molecular Function	GO:0016251	RNA polymerase II general transcription initiation factor activity	GTF2A2	IDA		Human	PMID:7958899
Molecular Function	GO:0001091	RNA polymerase II general transcription initiation factor binding	GTF2A2	IPI	UniProtKB:P52655	Human	PMID:8626665
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Gtf2a2	IPI	PR:Q8BIA3	Mouse	PMID:19235719
Molecular Function	GO:0017025	TBP-class protein binding	GTF2A2	IPI	UniProtKB:P20226	Human	PMID:7724559
Molecular Function	GO:0017025	TBP-class protein binding	GTF2A2	IPI	UniProtKB:P20226	Human	PMID:8626665
Cellular Component	GO:0030054	cell junction	GTF2A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	GTF2A2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GTF2A2	IDA		Human	PMID:10022900
Cellular Component	GO:0005672	transcription factor TFIIA complex	GTF2A2	IPI		Human	PMID:8626665
Cellular Component	GO:0005672	transcription factor TFIIA complex	GTF2A2	IDA		Human	PMID:7724559
Cellular Component	GO:0005672	transcription factor TFIIA complex	GTF2A2	IDA		Human	PMID:7958899
Cellular Component	GO:0005672	transcription factor TFIIA complex	GTF2A2	IDA		Human	PMID:7958900
Cellular Component	GO:0005669	transcription factor TFIID complex	GTF2A2	IDA		Human	PMID:27193682
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	GTF2A2	IDA		Human	PMID:10022900
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Gtf2a2	IMP		Rat	PMID:18171674|RGD:9590341
Biological Process	GO:0060261	positive regulation of transcription initiation by RNA polymerase II	GTF2A2	IDA		Human	PMID:11030333
Biological Process	GO:0051123	RNA polymerase II preinitiation complex assembly	GTF2A2	IDA		Human	PMID:7958899
Biological Process	GO:0051123	RNA polymerase II preinitiation complex assembly	GTF2A2	IDA		Human	PMID:8626665
Biological Process	GO:0006366	transcription by RNA polymerase II	GTF2A2	IDA		Human	PMID:27193682
Biological Process	GO:0006366	transcription by RNA polymerase II	GTF2A2	IDA		Human	PMID:7724559
Biological Process	GO:0006366	transcription by RNA polymerase II	GTF2A2	IDA		Human	PMID:7958900
Biological Process	GO:0006366	transcription by RNA polymerase II	GTF2A2	IDA		Human	PMID:8626665
Biological Process	GO:0006367	transcription initiation at RNA polymerase II promoter	GTF2A2	IDA		Human	PMID:7958899

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern