Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GSTM2
  • Mouse genes Gstm7
  • Rat genes Gstm7
  • Zfish genes gstm.1,gstm.2,gstm.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gstm7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	GSTM2	IPI	UniProtKB:P28161	Human	PMID:8373352
Molecular Function	GO:0005504	fatty acid binding	GSTM2	IPI	CHEBI:72639	Human	PMID:16624487
Molecular Function	GO:0043295	glutathione binding	GSTM2	IDA		Human	PMID:2034681
Molecular Function	GO:0043295	glutathione binding	GSTM2	IDA		Human	PMID:8373352
Molecular Function	GO:0004602	glutathione peroxidase activity	GSTM2	IDA		Human	PMID:16624487
Molecular Function	GO:0004364	glutathione transferase activity	GSTM2	IDA		Human	PMID:16549767
Molecular Function	GO:0004364	glutathione transferase activity	GSTM2	IDA		Human	PMID:2034681
Molecular Function	GO:0004364	glutathione transferase activity	GSTM2	IDA		Human	PMID:8373352
Molecular Function	GO:0004364	glutathione transferase activity	gstm.1	IDA		Zfish	PMID:25461745
Molecular Function	GO:0004364	glutathione transferase activity	gstm.3	IDA		Zfish	PMID:25461745
Molecular Function	GO:0005515	protein binding	GSTM2	IPI	UniProtKB:P19712:PRO_0000038050	Human	PMID:24965446
Molecular Function	GO:0005515	protein binding	GSTM2	IPI	UniProtKB:P46439	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	GSTM2	IPI	UniProtKB:P46439	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	GSTM2	IPI	UniProtKB:P28161	Human	PMID:8373352
Molecular Function	GO:0005102	signaling receptor binding	GSTM2	IPI	UniProtKB:E9Q401	Human	PMID:22406107
Cellular Component	GO:0005737	cytoplasm	GSTM2	IDA		Human	PMID:2034681
Cellular Component	GO:0005737	cytoplasm	GSTM2	IDA		Human	PMID:8373352
Cellular Component	GO:0005829	cytosol	GSTM2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	GSTM2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GSTM2	HDA		Human	PMID:23533145
Cellular Component	GO:0045171	intercellular bridge	GSTM2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016529	sarcoplasmic reticulum	GSTM2	IDA		Human	PMID:22406107
Biological Process	GO:0070458	cellular detoxification of nitrogen compound	GSTM2	IDA		Human	PMID:2034681
Biological Process	GO:0070458	cellular detoxification of nitrogen compound	GSTM2	IDA		Human	PMID:8373352
Biological Process	GO:0071313	cellular response to caffeine	GSTM2	IDA		Human	PMID:22406107
Biological Process	GO:0006749	glutathione metabolic process	GSTM2	IDA		Human	PMID:16549767
Biological Process	GO:0006749	glutathione metabolic process	GSTM2	IDA		Human	PMID:2034681
Biological Process	GO:0006749	glutathione metabolic process	GSTM2	IDA		Human	PMID:8373352
Biological Process	GO:0051122	hepoxilin biosynthetic process	GSTM2	IDA		Human	PMID:21046276
Biological Process	GO:0043651	linoleic acid metabolic process	GSTM2	IDA		Human	PMID:16624487
Biological Process	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	GSTM2	IDA		Human	PMID:17023043
Biological Process	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	GSTM2	IDA		Human	PMID:22406107
Biological Process	GO:0018916	nitrobenzene metabolic process	GSTM2	IDA		Human	PMID:2034681
Biological Process	GO:0018916	nitrobenzene metabolic process	GSTM2	IDA		Human	PMID:8373352
Biological Process	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity	GSTM2	IDA		Human	PMID:17023043
Biological Process	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	GSTM2	IDA		Human	PMID:17023043
Biological Process	GO:0042178	xenobiotic catabolic process	GSTM2	IDA		Human	PMID:16549767
Biological Process	GO:0042178	xenobiotic catabolic process	GSTM2	IDA		Human	PMID:2034681
Biological Process	GO:0042178	xenobiotic catabolic process	GSTM2	IDA		Human	PMID:8373352

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern