Comparative GO Graph (mouse, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes
  • Mouse genes Gsta4
  • Rat genes Gsta4
  • Zfish genes gsta.1,gsta.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gsta4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004364	glutathione transferase activity	gsta.2	IDA		Zfish	PMID:25461745
Molecular Function	GO:0097159	organic cyclic compound binding	Gsta4	IPI	CHEBI:34718	Rat	PMID:11018474|RGD:1641942
Molecular Function	GO:0015643	toxic substance binding	Gsta4	IPI	CHEBI:58968	Rat	PMID:11018474|RGD:1641942
Cellular Component	GO:0005737	cytoplasm	Gsta4	IDA		Rat	PMID:22160604|RGD:5687769
Cellular Component	GO:0005739	mitochondrion	Gsta4	IDA		Rat	PMID:9774145|RGD:5687770
Biological Process	GO:0071285	cellular response to lithium ion	Gsta4	IEP		Rat	PMID:18082333|RGD:2293846
Biological Process	GO:0009635	response to herbicide	Gsta4	IEP		Rat	PMID:20553223|RGD:5130934
Biological Process	GO:0035094	response to nicotine	Gsta4	IEP		Rat	PMID:9774145|RGD:5687770
Biological Process	GO:0010043	response to zinc ion	Gsta4	IEP		Rat	PMID:20553223|RGD:5130934

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern