Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPD1L
  • Mouse genes Gpd1l
  • Rat genes Gpd1l
  • Zfish genes gpd1l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpd1l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017080	sodium channel regulator activity	GPD1L	IMP		Human	PMID:17967977
Molecular Function	GO:0017080	sodium channel regulator activity	GPD1L	IMP		Human	PMID:19666841
Molecular Function	GO:0044325	transmembrane transporter binding	GPD1L	IPI	UniProtKB:Q14524	Human	PMID:19666841
Cellular Component	GO:0070062	extracellular exosome	GPD1L	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	Gpd1l	IDA		Mouse	MGI:MGI:5486550|PMID:17967977
Cellular Component	GO:0005886	plasma membrane	GPD1L	IDA		Human	PMID:17967977
Biological Process	GO:0019674	NAD metabolic process	GPD1L	IMP		Human	PMID:19745168
Biological Process	GO:0006734	NADH metabolic process	Gpd1l	IMP		Mouse	PMID:19745168
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	GPD1L	IMP		Human	PMID:19666841
Biological Process	GO:0090038	negative regulation of protein kinase C signaling	GPD1L	IMP		Human	PMID:19666841
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	GPD1L	IMP		Human	PMID:17967977
Biological Process	GO:2000010	positive regulation of protein localization to cell surface	GPD1L	IMP		Human	PMID:19666841
Biological Process	GO:0010765	positive regulation of sodium ion transport	GPD1L	IMP		Human	PMID:17967977
Biological Process	GO:0010765	positive regulation of sodium ion transport	GPD1L	IMP		Human	PMID:19666841
Biological Process	GO:0010765	positive regulation of sodium ion transport	GPD1L	IMP		Human	PMID:19745168
Biological Process	GO:0002027	regulation of heart rate	GPD1L	IMP		Human	PMID:17967977
Biological Process	GO:0002027	regulation of heart rate	GPD1L	IMP		Human	PMID:19666841
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	GPD1L	IMP		Human	PMID:17967977
Biological Process	GO:2000649	regulation of sodium ion transmembrane transporter activity	GPD1L	IMP		Human	PMID:19666841
Biological Process	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization	GPD1L	IMP		Human	PMID:17967977
Biological Process	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization	GPD1L	IMP		Human	PMID:19666841
Biological Process	GO:0086005	ventricular cardiac muscle cell action potential	GPD1L	IMP		Human	PMID:17967977
Biological Process	GO:0086005	ventricular cardiac muscle cell action potential	GPD1L	IMP		Human	PMID:19666841

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern