Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GK2
  • Mouse genes Gk2
  • Rat genes Gk2
  • Zfish genes zgc:172295
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gk2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GK2	IPI	UniProtKB:Q8N2A8	Human	PMID:28852571
Molecular Function	GO:0005515	protein binding	Gk2	IPI	UniProtKB:Q80X86	Mouse	MGI:MGI:6507113|PMID:33536340
Molecular Function	GO:0005515	protein binding	Gk2	IPI	UniProtKB:Q5SWZ9	Mouse	MGI:MGI:6355765|PMID:28852571
Cellular Component	GO:0070062	extracellular exosome	GK2	HDA		Human	PMID:19056867
Cellular Component	GO:0005741	mitochondrial outer membrane	Gk2	IDA		Mouse	MGI:MGI:6355765|PMID:28852571
Cellular Component	GO:0005739	mitochondrion	Gk2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0097225	sperm midpiece	GK2	IDA		Human	PMID:28852571
Cellular Component	GO:0097226	sperm mitochondrial sheath	Gk2	IDA		Mouse	MGI:MGI:6355765|PMID:28852571
Biological Process	GO:0030317	flagellated sperm motility	Gk2	IMP		Mouse	MGI:MGI:6359774|PMID:30662012
Biological Process	GO:0030317	flagellated sperm motility	Gk2	IMP		Mouse	MGI:MGI:6355765|PMID:28852571
Biological Process	GO:0120317	sperm mitochondrial sheath assembly	Gk2	IMP		Mouse	MGI:MGI:6355765|PMID:28852571
Biological Process	GO:0007283	spermatogenesis	Gk2	IMP		Mouse	MGI:MGI:6359774|PMID:30662012
Biological Process	GO:0007283	spermatogenesis	Gk2	IMP		Mouse	MGI:MGI:6355765|PMID:28852571

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern