Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GINS2
  • Mouse genes Gins2
  • Rat genes Gins2
  • Zfish genes gins2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gins2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	GINS2	IPI	UniProtKB:Q9BRT9	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	GINS2	IPI	UniProtKB:O96017	Human	PMID:17525332
Molecular Function	GO:0005515	protein binding	GINS2	IPI	UniProtKB:Q9BTE3	Human	PMID:22540012
Molecular Function	GO:0005515	protein binding	GINS2	IPI	UniProtKB:Q9BTE3	Human	PMID:24299456
Molecular Function	GO:0005515	protein binding	GINS2	IPI	UniProtKB:Q9BRT9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GINS2	IPI	UniProtKB:Q9BRT9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	GINS2	IPI	UniProtKB:Q9BRT9	Human	PMID:32296183
Cellular Component	GO:0071162	CMG complex	GINS2	IPI		Human	PMID:22474384
Cellular Component	GO:0000811	GINS complex	GINS2	IPI		Human	PMID:17417653
Cellular Component	GO:0005634	nucleus	GINS2	IDA		Human	PMID:22474384
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	GINS2	IDA		Human	PMID:22474384
Biological Process	GO:1903934	positive regulation of DNA primase activity	GINS2	IDA		Human	PMID:17170760
Biological Process	GO:1900264	positive regulation of DNA-directed DNA polymerase activity	GINS2	IDA		Human	PMID:17170760

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern