Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GEN1
  • Mouse genes Gen1
  • Rat genes Gen1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gen1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017108	5'-flap endonuclease activity	GEN1	IDA		Human	PMID:26578604
Molecular Function	GO:0008821	crossover junction DNA endonuclease activity	GEN1	IMP		Human	PMID:23108668
Molecular Function	GO:0008821	crossover junction DNA endonuclease activity	GEN1	IDA		Human	PMID:26578604
Molecular Function	GO:0008821	crossover junction DNA endonuclease activity	GEN1	IDA		Human	PMID:26682650
Molecular Function	GO:0008821	crossover junction DNA endonuclease activity	GEN1	IDA		Human	PMID:28049850
Molecular Function	GO:0000400	four-way junction DNA binding	GEN1	IDA		Human	PMID:26578604
Molecular Function	GO:0000400	four-way junction DNA binding	GEN1	IDA		Human	PMID:26682650
Molecular Function	GO:0000400	four-way junction DNA binding	GEN1	IDA		Human	PMID:28049850
Molecular Function	GO:0000287	magnesium ion binding	GEN1	IDA		Human	PMID:26682650
Molecular Function	GO:0042803	protein homodimerization activity	GEN1	IDA		Human	PMID:26578604
Cellular Component	GO:0005813	centrosome	GEN1	IDA		Human	PMID:23166748
Biological Process	GO:0000724	double-strand break repair via homologous recombination	GEN1	IMP		Human	PMID:23166748
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	GEN1	IMP		Human	PMID:23108668
Biological Process	GO:0010824	regulation of centrosome duplication	GEN1	IMP		Human	PMID:23108668
Biological Process	GO:0010824	regulation of centrosome duplication	GEN1	IMP		Human	PMID:23166748
Biological Process	GO:0031297	replication fork processing	GEN1	IDA		Human	PMID:26578604
Biological Process	GO:0071140	resolution of mitotic recombination intermediates	GEN1	IMP		Human	PMID:23108668
Biological Process	GO:0071139	resolution of recombination intermediates	GEN1	IMP		Human	PMID:24080495

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern