Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GCSAM
  • Mouse genes Gcsam
  • Rat genes Gcsam
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gcsam

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	GCSAM	IPI	UniProtKB:P60709	Human	PMID:17823310
Molecular Function	GO:0045159	myosin II binding	GCSAM	IPI	UniProtKB:Q9UKX2	Human	PMID:17823310
Molecular Function	GO:0005515	protein binding	GCSAM	IPI	UniProtKB:O15085	Human	PMID:20844236
Molecular Function	GO:0005515	protein binding	GCSAM	IPI	UniProtKB:Q9NZN5	Human	PMID:20844236
Molecular Function	GO:0005515	protein binding	GCSAM	IPI	UniProtKB:Q92624	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	GCSAM	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GCSAM	IPI	UniProtKB:Q92624	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GCSAM	IPI	UniProtKB:Q9BXS5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GCSAM	IPI	UniProtKB:Q9NZN8	Human	PMID:32296183
Molecular Function	GO:0019901	protein kinase binding	GCSAM	IPI	UniProtKB:P43405	Human	PMID:23299888
Biological Process	GO:2000402	negative regulation of lymphocyte migration	GCSAM	IMP		Human	PMID:17823310
Biological Process	GO:0050855	regulation of B cell receptor signaling pathway	GCSAM	IMP		Human	PMID:23299888

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern