Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FTMT
  • Mouse genes Ftmt
  • Rat genes Ftmt
  • Zfish genes fth1a,fth1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ftmt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004322	ferroxidase activity	FTMT	IDA		Human	PMID:11323407
Molecular Function	GO:0004322	ferroxidase activity	FTMT	IDA		Human	PMID:15201052
Molecular Function	GO:0004322	ferroxidase activity	Ftmt	IDA		Mouse	MGI:MGI:7310195|PMID:15201052
Molecular Function	GO:0005506	iron ion binding	FTMT	IDA		Human	PMID:15201052
Cellular Component	GO:0005739	mitochondrion	FTMT	IDA		Human	PMID:11323407
Cellular Component	GO:0005739	mitochondrion	Ftmt	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Ftmt	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005634	nucleus	FTMT	HDA		Human	PMID:21630459
Biological Process	GO:0006879	intracellular iron ion homeostasis	FTMT	IDA		Human	PMID:11323407
Biological Process	GO:0006879	intracellular iron ion homeostasis	FTMT	IDA		Human	PMID:18160053
Biological Process	GO:1904234	positive regulation of aconitate hydratase activity	FTMT	IGI	UniProtKB:Q16595	Human	PMID:18160053
Biological Process	GO:0008284	positive regulation of cell population proliferation	FTMT	IDA		Human	PMID:18160053
Biological Process	GO:0051349	positive regulation of lyase activity	FTMT	IDA		Human	PMID:18160053
Biological Process	GO:1904231	positive regulation of succinate dehydrogenase activity	FTMT	IGI	UniProtKB:Q16595	Human	PMID:18160053

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern