Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FRMD5
  • Mouse genes Frmd5
  • Rat genes Frmd5
  • Zfish genes frmd5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Frmd5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005178	integrin binding	FRMD5	IDA		Human	PMID:25448675
Molecular Function	GO:0005515	protein binding	FRMD5	IPI	UniProtKB:O60716	Human	PMID:22846708
Molecular Function	GO:0005515	protein binding	FRMD5	IPI	UniProtKB:P18084	Human	PMID:25448675
Molecular Function	GO:0005515	protein binding	FRMD5	IPI	UniProtKB:Q13464	Human	PMID:25448675
Molecular Function	GO:0019901	protein kinase binding	FRMD5	IDA		Human	PMID:25448675
Cellular Component	GO:0005912	adherens junction	FRMD5	IDA		Human	PMID:22846708
Biological Process	GO:2000146	negative regulation of cell motility	FRMD5	IMP		Human	PMID:25448675
Biological Process	GO:0045785	positive regulation of cell adhesion	FRMD5	IMP		Human	PMID:25448675
Biological Process	GO:0030334	regulation of cell migration	FRMD5	IMP		Human	PMID:22846708

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern