Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXL12
  • Mouse genes Fbxl12
  • Rat genes Fbxl12
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxl12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FBXL12	IPI	UniProtKB:P49918	Human	PMID:18660753
Molecular Function	GO:0005515	protein binding	FBXL12	IPI	UniProtKB:P63208	Human	PMID:18660753
Molecular Function	GO:0005515	protein binding	FBXL12	IPI	UniProtKB:Q9H0A6	Human	PMID:21163940
Molecular Function	GO:0005515	protein binding	FBXL12	IPI	UniProtKB:Q8NF50-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXL12	IPI	UniProtKB:Q8TBB1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXL12	IPI	UniProtKB:P63208	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	FBXL12	IPI	UniProtKB:P57678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXL12	IPI	UniProtKB:P63208	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Fbxl12	IDA		Mouse	PMID:10531037
Cellular Component	GO:0000151	ubiquitin ligase complex	Fbxl12	IPI	PR:Q9WTX5	Mouse	PMID:10531037
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Fbxl12	IPI	PR:Q9WTX5	Mouse	PMID:10531037

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern