Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FANCI
  • Mouse genes Fanci
  • Rat genes Fanci
  • Zfish genes fanci
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fanci

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070182	DNA polymerase binding	FANCI	IPI	UniProtKB:Q7Z5Q5	Human	PMID:19995904
Molecular Function	GO:0005515	protein binding	FANCI	IPI	UniProtKB:Q9BXW9	Human	PMID:17460694
Molecular Function	GO:0005515	protein binding	FANCI	IPI	UniProtKB:Q9BXW9	Human	PMID:20603015
Molecular Function	GO:0005515	protein binding	FANCI	IPI	UniProtKB:Q9Y2M0	Human	PMID:20603015
Cellular Component	GO:0005737	cytoplasm	FANCI	IDA		Human	PMID:18445686
Cellular Component	GO:0005829	cytosol	FANCI	IDA		Human	GO_REF:0000052
Cellular Component	GO:1990391	DNA repair complex	FANCI	IPI		Human	PMID:32269332
Cellular Component	GO:0016020	membrane	FANCI	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	FANCI	IDA		Human	GO_REF:0000052
Biological Process	GO:0031398	positive regulation of protein ubiquitination	FANCI	IDA		Human	PMID:18029348

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern