Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXOSC9
  • Mouse genes Exosc9
  • Rat genes Exosc9
  • Zfish genes exosc9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Exosc9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	EXOSC9	IDA		Human	PMID:11782436
Molecular Function	GO:0005515	protein binding	EXOSC9	IPI	UniProtKB:Q9NPD3	Human	PMID:12788944
Molecular Function	GO:0005515	protein binding	EXOSC9	IPI	UniProtKB:Q9NPD3	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC9	IPI	UniProtKB:Q9NPD3	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC9	IPI	UniProtKB:Q7Z333	Human	PMID:24105744
Molecular Function	GO:0005515	protein binding	EXOSC9	IPI	UniProtKB:Q9NPD3	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC9	IPI	UniProtKB:Q9NPD3	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC9	IPI	UniProtKB:Q9NPD3	Human	PMID:30021884
Molecular Function	GO:0003723	RNA binding	EXOSC9	HDA		Human	PMID:22658674
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Exosc9	IPI	RGD:1351290	Rat	PMID:9148967|RGD:10755760
Cellular Component	GO:0005737	cytoplasm	EXOSC9	IDA		Human	PMID:17545563
Cellular Component	GO:0005829	cytosol	EXOSC9	IDA		Human	PMID:20531386
Cellular Component	GO:0000178	exosome (RNase complex)	EXOSC9	IDA		Human	PMID:20531389
Cellular Component	GO:0070062	extracellular exosome	EXOSC9	HDA		Human	PMID:18570454
Cellular Component	GO:0000228	nuclear chromosome	EXOSC9	IDA		Human	PMID:24105744
Cellular Component	GO:0000176	nuclear exosome (RNase complex)	EXOSC9	IDA		Human	PMID:22791713
Cellular Component	GO:0005730	nucleolus	EXOSC9	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	EXOSC9	IDA		Human	PMID:20531386
Cellular Component	GO:0005730	nucleolus	EXOSC9	IDA		Human	PMID:24105744
Cellular Component	GO:0005654	nucleoplasm	EXOSC9	IDA		Human	PMID:24105744
Cellular Component	GO:0005634	nucleus	EXOSC9	IDA		Human	PMID:17545563
Cellular Component	GO:0005634	nucleus	EXOSC9	IDA		Human	PMID:20531386
Biological Process	GO:0043928	exonucleolytic catabolism of deadenylated mRNA	EXOSC9	IMP		Human	PMID:11782436
Biological Process	GO:0071028	nuclear mRNA surveillance	EXOSC9	IMP		Human	PMID:17545563
Biological Process	GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process	EXOSC9	IMP		Human	PMID:16455498
Biological Process	GO:0000956	nuclear-transcribed mRNA catabolic process	EXOSC9	IMP		Human	PMID:17545563
Biological Process	GO:0030307	positive regulation of cell growth	EXOSC9	IMP		Human	PMID:17545563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Exosc9	IDA		Rat	PMID:9148967|RGD:10755760
Biological Process	GO:0006401	RNA catabolic process	EXOSC9	IDA		Human	PMID:17174896
Biological Process	GO:0006401	RNA catabolic process	EXOSC9	IDA		Human	PMID:20531386
Biological Process	GO:0006396	RNA processing	EXOSC9	IDA		Human	PMID:17174896
Biological Process	GO:0006396	RNA processing	EXOSC9	IDA		Human	PMID:20531386

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern