Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXD2
  • Mouse genes Exd2
  • Rat genes Exd2
  • Zfish genes exd2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Exd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008408	3'-5' exonuclease activity	EXD2	IDA		Human	PMID:26807646
Molecular Function	GO:0008408	3'-5' exonuclease activity	EXD2	IMP		Human	PMID:31255466
Molecular Function	GO:0008296	3'-5'-DNA exonuclease activity	EXD2	IDA		Human	PMID:31127291
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	EXD2	IDA		Human	PMID:31127291
Molecular Function	GO:0000287	magnesium ion binding	EXD2	IDA		Human	PMID:31127291
Molecular Function	GO:0030145	manganese ion binding	EXD2	IDA		Human	PMID:31127291
Molecular Function	GO:0005515	protein binding	EXD2	IPI	UniProtKB:P38398,UniProtKB:P49959,UniProtKB:Q99708	Human	PMID:26807646
Molecular Function	GO:0005515	protein binding	EXD2	IPI	UniProtKB:Q99708	Human	PMID:26807646
Molecular Function	GO:0042803	protein homodimerization activity	EXD2	IDA		Human	PMID:31127291
Molecular Function	GO:0008310	single-stranded DNA 3'-5' DNA exonuclease activity	EXD2	IDA		Human	PMID:26807646
Cellular Component	GO:0045111	intermediate filament cytoskeleton	EXD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005741	mitochondrial outer membrane	EXD2	IDA		Human	PMID:29599527
Cellular Component	GO:0005741	mitochondrial outer membrane	EXD2	IDA		Human	PMID:31127291
Cellular Component	GO:0005739	mitochondrion	EXD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0090734	site of DNA damage	EXD2	IDA		Human	PMID:31255466
Biological Process	GO:0000729	DNA double-strand break processing	EXD2	IDA		Human	PMID:26807646
Biological Process	GO:0006302	double-strand break repair	EXD2	IDA		Human	PMID:26807646
Biological Process	GO:0000724	double-strand break repair via homologous recombination	EXD2	IDA		Human	PMID:26807646
Biological Process	GO:0090305	nucleic acid phosphodiester bond hydrolysis	EXD2	IDA		Human	PMID:26807646
Biological Process	GO:0031297	replication fork processing	EXD2	IMP		Human	PMID:31255466

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern