Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ENAM
  • Mouse genes Enam
  • Rat genes Enam
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Enam

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ENAM	IPI	UniProtKB:Q8IXL6	Human	PMID:25789606
Molecular Function	GO:0030345	structural constituent of tooth enamel	Enam	IDA		Mouse	PMID:24603688
Cellular Component	GO:0031012	extracellular matrix	Enam	IDA		Mouse	PMID:24603688
Biological Process	GO:0036305	ameloblast differentiation	Enam	IMP	MGI:MGI:3796583	Mouse	PMID:24603688
Biological Process	GO:0097186	amelogenesis	Enam	IMP	MGI:MGI:3796583	Mouse	PMID:24603688
Biological Process	GO:0097186	amelogenesis	Enam	IMP	MGI:MGI:3055586	Mouse	PMID:15649948
Biological Process	GO:0097186	amelogenesis	Enam	IMP		Mouse	PMID:22813216
Biological Process	GO:0097186	amelogenesis	Enam	IMP	MGI:MGI:3796583	Mouse	PMID:18252720
Biological Process	GO:0097186	amelogenesis	Enam	IMP	MGI:MGI:3055587	Mouse	PMID:15649948
Biological Process	GO:0097186	amelogenesis	Enam	IMP	MGI:MGI:3055582	Mouse	PMID:15649948
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Enam	IMP	MGI:MGI:3512772	Mouse	PMID:15271968
Biological Process	GO:0070175	positive regulation of enamel mineralization	Enam	IMP	MGI:MGI:3796583	Mouse	PMID:24603688
Biological Process	GO:0022604	regulation of cell morphogenesis	Enam	IMP	MGI:MGI:3796583	Mouse	PMID:24603688

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern