Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF4A2
  • Mouse genes Eif4a2
  • Rat genes Eif4a2
  • Zfish genes eif4a2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif4a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016887	ATP hydrolysis activity	EIF4A2	IDA		Human	PMID:11922617
Molecular Function	GO:0005515	protein binding	EIF4A2	IPI	UniProtKB:P27958:PRO_0000037577	Human	PMID:11922617
Molecular Function	GO:0005515	protein binding	EIF4A2	IPI	UniProtKB:P27958:PRO_0000037577	Human	PMID:17229681
Molecular Function	GO:0005515	protein binding	EIF4A2	IPI	UniProtKB:P04792	Human	PMID:25277244
Molecular Function	GO:0005515	protein binding	EIF4A2	IPI	UniProtKB:Q53EL6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF4A2	IPI	UniProtKB:Q7L190	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF4A2	IPI	UniProtKB:Q7RTY1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF4A2	IPI	UniProtKB:Q9HCM9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF4A2	IPI	UniProtKB:Q9NQ86	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF4A2	IPI	UniProtKB:Q9UI26	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF4A2	IPI	UniProtKB:Q9Y2D8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF4A2	IPI	UniProtKB:Q9HCM9	Human	PMID:31515488
Molecular Function	GO:0003723	RNA binding	EIF4A2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	EIF4A2	HDA		Human	PMID:22681889
Cellular Component	GO:0048471	perinuclear region of cytoplasm	EIF4A2	IDA		Human	PMID:11922617
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Eif4a2	IEP		Mouse	PMID:20439489
Biological Process	GO:1900260	negative regulation of RNA-dependent RNA polymerase activity	EIF4A2	IDA		Human	PMID:11922617

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern