Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF1
  • Mouse genes Eif1
  • Rat genes Eif1
  • Zfish genes eif1,eif1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EIF1	IPI	UniProtKB:Q14152	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF1	IPI	UniProtKB:Q99613	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF1	IPI	UniProtKB:Q04637	Human	PMID:29987188
Molecular Function	GO:0005515	protein binding	EIF1	IPI	UniProtKB:Q99613	Human	PMID:29987188
Molecular Function	GO:0043024	ribosomal small subunit binding	EIF1	IDA		Human	PMID:14600024
Molecular Function	GO:0003723	RNA binding	EIF1	HDA		Human	PMID:22681889
Molecular Function	GO:0003743	translation initiation factor activity	EIF1	IDA		Human	PMID:12435632
Molecular Function	GO:0003743	translation initiation factor activity	EIF1	IDA		Human	PMID:29987188
Cellular Component	GO:0005737	cytoplasm	EIF1	IDA		Human	PMID:12426392
Cellular Component	GO:0016282	eukaryotic 43S preinitiation complex	EIF1	IDA		Human	PMID:9732867
Cellular Component	GO:0033290	eukaryotic 48S preinitiation complex	EIF1	IDA		Human	PMID:12435632
Cellular Component	GO:0033290	eukaryotic 48S preinitiation complex	EIF1	IDA		Human	PMID:9752867
Cellular Component	GO:0005634	nucleus	EIF1	IDA		Human	PMID:12426392
Biological Process	GO:0009048	dosage compensation by inactivation of X chromosome	Eif1	IMP		Mouse	PMID:16789828
Biological Process	GO:0006446	regulation of translational initiation	EIF1	IDA		Human	PMID:22156057
Biological Process	GO:0006413	translational initiation	EIF1	IDA		Human	PMID:12435632
Biological Process	GO:0006413	translational initiation	EIF1	IDA		Human	PMID:29987188
Biological Process	GO:0006413	translational initiation	EIF1	IDA		Human	PMID:9732867

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern