Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DPM2
  • Mouse genes Dpm2
  • Rat genes Dpm2
  • Zfish genes dpm1,dpm2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dpm2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity	Dpm2	IDA		Rat	PMID:9724629|RGD:69827
Molecular Function	GO:0008047	enzyme activator activity	DPM2	IDA		Human	PMID:10835346
Molecular Function	GO:0030234	enzyme regulator activity	Dpm2	IDA		Rat	PMID:9724629|RGD:69827
Molecular Function	GO:0005515	protein binding	DPM2	IPI	UniProtKB:Q9P2X0	Human	PMID:10835346
Molecular Function	GO:0005515	protein binding	DPM2	IPI	UniProtKB:P37287	Human	PMID:10944123
Molecular Function	GO:0005515	protein binding	DPM2	IPI	UniProtKB:Q92535	Human	PMID:10944123
Molecular Function	GO:0005515	protein binding	DPM2	IPI	UniProtKB:Q9BRB3	Human	PMID:10944123
Molecular Function	GO:0005515	protein binding	DPM2	IPI	UniProtKB:Q9P2X0	Human	PMID:10944123
Molecular Function	GO:0005515	protein binding	DPM2	IPI	UniProtKB:P37287	Human	PMID:16162815
Molecular Function	GO:0005515	protein binding	Dpm2	IPI	UniProtKB:Q9P2X0	Rat	PMID:10835346|RGD:8553280
Cellular Component	GO:0033185	dolichol-phosphate-mannose synthase complex	DPM2	IPI		Human	PMID:10835346
Cellular Component	GO:0033185	dolichol-phosphate-mannose synthase complex	DPM2	IDA		Human	PMID:10835346
Cellular Component	GO:0033185	dolichol-phosphate-mannose synthase complex	Dpm2	IDA		Rat	PMID:9724629|RGD:69827
Cellular Component	GO:0005783	endoplasmic reticulum	Dpm2	IDA		Rat	PMID:9724629|RGD:69827
Cellular Component	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	DPM2	IPI		Human	PMID:16162815
Cellular Component	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	DPM2	IDA		Human	PMID:10944123
Cellular Component	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	DPM2	IDA		Human	PMID:16162815
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Dpm2	IDA		Rat	PMID:9724629|RGD:69827
Biological Process	GO:0019348	dolichol metabolic process	DPM2	IDA		Human	PMID:10835346
Biological Process	GO:0019348	dolichol metabolic process	Dpm2	IDA		Rat	PMID:9724629|RGD:69827
Biological Process	GO:0006506	GPI anchor biosynthetic process	DPM2	IDA		Human	PMID:10835346
Biological Process	GO:0006506	GPI anchor biosynthetic process	DPM2	IDA		Human	PMID:16162815
Biological Process	GO:0006506	GPI anchor biosynthetic process	Dpm2	IDA		Rat	PMID:9724629|RGD:69827
Biological Process	GO:0061061	muscle structure development	dpm2	IMP	ZFIN:ZDB-MRPHLNO-160907-11	Zfish	PMID:27291147
Biological Process	GO:0061061	muscle structure development	dpm1	IMP	ZFIN:ZDB-MRPHLNO-160907-9	Zfish	PMID:27291147
Biological Process	GO:0031647	regulation of protein stability	DPM2	IPI	UniProtKB:Q9P2X0	Human	PMID:10835346

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern