Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DMPK
  • Mouse genes Dmpk
  • Rat genes Dmpk
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dmpk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	DMPK	IDA		Human	PMID:10913253
Molecular Function	GO:0017020	myosin phosphatase regulator activity	DMPK	IDA		Human	PMID:11287000
Molecular Function	GO:0005515	protein binding	DMPK	IPI	UniProtKB:P26678	Human	PMID:15598648
Molecular Function	GO:0005515	protein binding	DMPK	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	DMPK	IPI	UniProtKB:P02545	Human	PMID:21949239
Molecular Function	GO:0005515	protein binding	DMPK	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Dmpk	IPI	PR:O35900	Mouse	PMID:8851885
Molecular Function	GO:0004674	protein serine/threonine kinase activity	DMPK	IDA		Human	PMID:10913253
Molecular Function	GO:0004674	protein serine/threonine kinase activity	DMPK	IDA		Human	PMID:11287000
Cellular Component	GO:0005829	cytosol	Dmpk	IDA		Mouse	MGI:MGI:3529390|PMID:15684391
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Dmpk	IDA		Mouse	MGI:MGI:3529390|PMID:15684391
Cellular Component	GO:0016020	membrane	Dmpk	IDA		Rat	PMID:20188867|RGD:5686774
Cellular Component	GO:0005741	mitochondrial outer membrane	DMPK	IDA		Human	PMID:15684391
Cellular Component	GO:0005741	mitochondrial outer membrane	Dmpk	IDA		Mouse	MGI:MGI:3529390|PMID:15684391
Cellular Component	GO:0031965	nuclear membrane	Dmpk	IDA		Mouse	MGI:MGI:3529390|PMID:15684391
Cellular Component	GO:0005886	plasma membrane	Dmpk	IDA		Mouse	MGI:MGI:3806406|PMID:18729234
Cellular Component	GO:0033017	sarcoplasmic reticulum membrane	Dmpk	IDA		Mouse	MGI:MGI:3575053|PMID:15598648
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Dmpk	IMP		Mouse	MGI:MGI:1097019|PMID:9294109
Biological Process	GO:0010657	muscle cell apoptotic process	DMPK	IDA		Human	PMID:18729234
Biological Process	GO:0006998	nuclear envelope organization	DMPK	IMP		Human	PMID:21949239
Biological Process	GO:0006998	nuclear envelope organization	Dmpk	IMP		Mouse	MGI:MGI:5298442|PMID:21949239
Biological Process	GO:0006468	protein phosphorylation	DMPK	IDA		Human	PMID:10913253
Biological Process	GO:0006468	protein phosphorylation	DMPK	IDA		Human	PMID:11287000
Biological Process	GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	Dmpk	IMP	MGI:MGI:2182402	Mouse	PMID:11526199
Biological Process	GO:0008016	regulation of heart contraction	DMPK	IDA		Human	PMID:15598648
Biological Process	GO:0008016	regulation of heart contraction	Dmpk	IDA		Mouse	MGI:MGI:3575053|PMID:15598648
Biological Process	GO:0010830	regulation of myotube differentiation	Dmpk	IMP		Mouse	MGI:MGI:3806406|PMID:18729234
Biological Process	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling	Dmpk	IMP		Mouse	MGI:MGI:1097019|PMID:9294109
Biological Process	GO:0002028	regulation of sodium ion transport	Dmpk	IMP	MGI:MGI:2182402	Mouse	PMID:11526199
Biological Process	GO:0051823	regulation of synapse structural plasticity	Dmpk	IMP		Mouse	MGI:MGI:3608373|PMID:12612014

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern