Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DIS3L
  • Mouse genes Dis3l
  • Rat genes Dis3l
  • Zfish genes dis3l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dis3l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	DIS3L	IMP		Human	PMID:20531386
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	DIS3L	IDA		Human	PMID:20531389
Molecular Function	GO:0019899	enzyme binding	DIS3L	IPI	UniProtKB:Q9NPD3	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	DIS3L	IPI	UniProtKB:Q9NQT5	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	DIS3L	IPI	UniProtKB:Q9NQT5	Human	PMID:20531389
Molecular Function	GO:0005515	protein binding	DIS3L	IPI	UniProtKB:Q9NQT5	Human	PMID:23756462
Molecular Function	GO:0005515	protein binding	DIS3L	IPI	UniProtKB:Q9NQT5	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	DIS3L	IPI	UniProtKB:Q9NQT5	Human	PMID:26496610
Cellular Component	GO:0005813	centrosome	DIS3L	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000177	cytoplasmic exosome (RNase complex)	DIS3L	IDA		Human	PMID:20531386
Cellular Component	GO:0000177	cytoplasmic exosome (RNase complex)	DIS3L	IDA		Human	PMID:20531389
Cellular Component	GO:0005829	cytosol	DIS3L	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	DIS3L	IDA		Human	PMID:20531386
Cellular Component	GO:0005886	plasma membrane	DIS3L	IDA		Human	GO_REF:0000052
Biological Process	GO:0006401	RNA catabolic process	DIS3L	IDA		Human	PMID:20531386
Biological Process	GO:0006396	RNA processing	DIS3L	IDA		Human	PMID:20531386
Biological Process	GO:0016075	rRNA catabolic process	DIS3L	IMP		Human	PMID:20368444
Biological Process	GO:0016075	rRNA catabolic process	DIS3L	IDA		Human	PMID:20531389

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern