Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DDX60
  • Mouse genes Ddx60
  • Rat genes Ddx60
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddx60

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003690	double-stranded DNA binding	DDX60	IDA		Human	PMID:21791617
Molecular Function	GO:0003725	double-stranded RNA binding	DDX60	IDA		Human	PMID:21791617
Molecular Function	GO:0005515	protein binding	DDX60	IPI	UniProtKB:O95786	Human	PMID:21791617
Molecular Function	GO:0005515	protein binding	DDX60	IPI	UniProtKB:Q96C10	Human	PMID:21791617
Molecular Function	GO:0005515	protein binding	DDX60	IPI	UniProtKB:Q9BYX4	Human	PMID:21791617
Molecular Function	GO:0005515	protein binding	DDX60	IPI	UniProtKB:Q9NPD3	Human	PMID:21791617
Molecular Function	GO:0005515	protein binding	DDX60	IPI	UniProtKB:Q9Y3B2	Human	PMID:21791617
Molecular Function	GO:0005515	protein binding	DDX60	IPI	UniProtKB:P60228	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	Ddx60	IPI	PR:Q9DAA6	Mouse	PMID:21791617
Molecular Function	GO:0005515	protein binding	Ddx60	IPI	PR:Q6Q899	Mouse	PMID:21791617
Molecular Function	GO:0005515	protein binding	Ddx60	IPI	PR:Q8R5F7	Mouse	PMID:21791617
Molecular Function	GO:0005515	protein binding	Ddx60	IPI	PR:Q921I9	Mouse	PMID:21791617
Molecular Function	GO:0003723	RNA binding	Ddx60	IDA		Mouse	PMID:21791617
Molecular Function	GO:0003727	single-stranded RNA binding	DDX60	IDA		Human	PMID:21791617
Cellular Component	GO:0005737	cytoplasm	DDX60	IDA		Human	PMID:21791617
Cellular Component	GO:0005737	cytoplasm	Ddx60	IDA		Mouse	PMID:21791617
Cellular Component	GO:0005829	cytosol	DDX60	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045111	intermediate filament cytoskeleton	DDX60	IDA		Human	GO_REF:0000052
Biological Process	GO:0051607	defense response to virus	Ddx60	IDA		Mouse	PMID:21791617
Biological Process	GO:1900245	positive regulation of MDA-5 signaling pathway	DDX60	IMP		Human	PMID:21791617
Biological Process	GO:1900246	positive regulation of RIG-I signaling pathway	DDX60	IMP		Human	PMID:21791617
Biological Process	GO:0009615	response to virus	DDX60	IDA		Human	PMID:21791617

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern