Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYP4F2,CYP4F3
  • Mouse genes Cyp4f18
  • Rat genes Cyp4f18
  • Zfish genes cyp4f3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyp4f18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0018685	alkane 1-monooxygenase activity	CYP4F2	IDA		Human	PMID:18433732
Molecular Function	GO:0052871	alpha-tocopherol omega-hydroxylase activity	CYP4F2	IDA		Human	PMID:20861217
Molecular Function	GO:0008392	arachidonic acid epoxygenase activity	CYP4F2	IDA		Human	PMID:20861217
Molecular Function	GO:0008392	arachidonic acid epoxygenase activity	CYP4F2	IDA		Human	PMID:9618440
Molecular Function	GO:0052869	arachidonic acid omega-hydroxylase activity	CYP4F2	IDA		Human	PMID:10660572
Molecular Function	GO:0052869	arachidonic acid omega-hydroxylase activity	CYP4F2	IDA		Human	PMID:9618440
Molecular Function	GO:0050051	leukotriene-B4 20-monooxygenase activity	CYP4F2	IDA		Human	PMID:8026587
Molecular Function	GO:0050051	leukotriene-B4 20-monooxygenase activity	CYP4F2	IDA		Human	PMID:9799565
Molecular Function	GO:0120319	long-chain fatty acid omega-1 hydroxylase activity	Cyp4f18	IDA		Mouse	MGI:MGI:3640626|PMID:16380383
Molecular Function	GO:0102033	long-chain fatty acid omega-hydroxylase activity	CYP4F2	IDA		Human	PMID:15145985
Molecular Function	GO:0102033	long-chain fatty acid omega-hydroxylase activity	CYP4F2	IDA		Human	PMID:18577768
Molecular Function	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	CYP4F2	IDA		Human	PMID:19297519
Molecular Function	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	CYP4F2	IDA		Human	PMID:24138531
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:O43889-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:O15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:O95214	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:P15941-11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:P48165	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q03395	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q12999	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q15546	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q53GL0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q7Z7G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q8NDX2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q8WY91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q96BA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q96DZ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q96KC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q96KR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q96MV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q96MV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q96QE2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q9BRK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q9BZV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q9H2K0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q9NPE6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q9NW97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q9NX18	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYP4F2	IPI	UniProtKB:Q9Y320	Human	PMID:32296183
Molecular Function	GO:0052872	tocotrienol omega-hydroxylase activity	CYP4F2	IDA		Human	PMID:20861217
Cellular Component	GO:0016324	apical plasma membrane	CYP4F2	IDA		Human	PMID:10660572
Cellular Component	GO:0005737	cytoplasm	CYP4F2	IDA		Human	PMID:10660572
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CYP4F2	IDA		Human	PMID:10660572
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CYP4F2	IDA		Human	PMID:20861217
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CYP4F2	IDA		Human	PMID:24138531
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CYP4F2	IDA		Human	PMID:9618440
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CYP4F2	IDA		Human	PMID:9799565
Biological Process	GO:0019369	arachidonic acid metabolic process	CYP4F2	IDA		Human	PMID:10660572
Biological Process	GO:0019373	epoxygenase P450 pathway	CYP4F2	IDA		Human	PMID:20861217
Biological Process	GO:0019373	epoxygenase P450 pathway	CYP4F2	IDA		Human	PMID:9618440
Biological Process	GO:0010430	fatty acid omega-oxidation	CYP4F2	IDA		Human	PMID:18577768
Biological Process	GO:0036101	leukotriene B4 catabolic process	CYP4F2	IDA		Human	PMID:10492403
Biological Process	GO:0036101	leukotriene B4 catabolic process	CYP4F2	IDA		Human	PMID:8026587
Biological Process	GO:0036101	leukotriene B4 catabolic process	CYP4F2	IDA		Human	PMID:9799565
Biological Process	GO:0036102	leukotriene B4 metabolic process	Cyp4f18	IDA		Mouse	MGI:MGI:3640626|PMID:16380383
Biological Process	GO:0001676	long-chain fatty acid metabolic process	CYP4F2	IDA		Human	PMID:18433732
Biological Process	GO:0042361	menaquinone catabolic process	CYP4F2	IDA		Human	PMID:24138531
Biological Process	GO:0032304	negative regulation of icosanoid secretion	CYP4F2	IMP		Human	PMID:18391101
Biological Process	GO:0097267	omega-hydroxylase P450 pathway	CYP4F2	IDA		Human	PMID:9799565
Biological Process	GO:0042376	phylloquinone catabolic process	CYP4F2	IDA		Human	PMID:24138531
Biological Process	GO:0032305	positive regulation of icosanoid secretion	CYP4F2	IMP		Human	PMID:17341693
Biological Process	GO:0003095	pressure natriuresis	CYP4F2	IEP		Human	PMID:10660572
Biological Process	GO:0008217	regulation of blood pressure	CYP4F2	IMP		Human	PMID:18391101
Biological Process	GO:0003091	renal water homeostasis	CYP4F2	IEP		Human	PMID:10660572
Biological Process	GO:0055078	sodium ion homeostasis	CYP4F2	IEP		Human	PMID:10660572
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	CYP4F2	IDA		Human	PMID:18433732
Biological Process	GO:0042360	vitamin E metabolic process	CYP4F2	IDA		Human	PMID:20861217
Biological Process	GO:0042377	vitamin K catabolic process	CYP4F2	IDA		Human	PMID:19297519
Biological Process	GO:0042377	vitamin K catabolic process	CYP4F2	IDA		Human	PMID:24138531
Biological Process	GO:0006805	xenobiotic metabolic process	CYP4F2	IMP		Human	PMID:21084764
Biological Process	GO:0006805	xenobiotic metabolic process	CYP4F2	IMP		Human	PMID:21127708

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern