Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CXXC4
  • Mouse genes Cxxc4
  • Rat genes Cxxc4
  • Zfish genes cxxc4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cxxc4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008327	methyl-CpG binding	CXXC4	IDA		Human	PMID:29276034
Molecular Function	GO:0030165	PDZ domain binding	CXXC4	IPI	UniProtKB:O14640	Human	PMID:11113207
Molecular Function	GO:0030165	PDZ domain binding	CXXC4	IPI	UniProtKB:Q92997	Human	PMID:11113207
Molecular Function	GO:0030165	PDZ domain binding	Cxxc4	IPI	UniProtKB:O14640	Rat	PMID:11113207|RGD:68802
Molecular Function	GO:0030165	PDZ domain binding	Cxxc4	IPI	RGD:733043	Rat	PMID:15313210|RGD:2303370
Molecular Function	GO:0005515	protein binding	Cxxc4	IPI	PR:Q8BG87	Mouse	PMID:23690950
Molecular Function	GO:0005515	protein binding	Cxxc4	IPI	UniProtKB:O14640	Rat	PMID:11113207|RGD:68802
Molecular Function	GO:0008270	zinc ion binding	CXXC4	IDA		Human	PMID:29276034
Cellular Component	GO:0005737	cytoplasm	CXXC4	IDA		Human	PMID:11113207
Cellular Component	GO:0005737	cytoplasm	Cxxc4	IDA		Mouse	PMID:11113207
Cellular Component	GO:0031410	cytoplasmic vesicle	CXXC4	IDA		Human	PMID:11113207
Cellular Component	GO:0031410	cytoplasmic vesicle	Cxxc4	IDA		Mouse	PMID:11113207
Cellular Component	GO:0005634	nucleus	Cxxc4	IDA		Mouse	PMID:23690950
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	CXXC4	IDA		Human	PMID:11113207
Biological Process	GO:0016055	Wnt signaling pathway	Cxxc4	IPI	PR:P51141	Mouse	PMID:11113207

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern