Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CRB3
  • Mouse genes Crb3
  • Rat genes Crb3
  • Zfish genes crb3a,crb3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Crb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CRB3	IPI	UniProtKB:Q9HCM4	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	CRB3	IPI	UniProtKB:P25788	Human	PMID:25416956
Molecular Function	GO:0019904	protein domain specific binding	CRB3	IPI	UniProtKB:Q8N3R9	Human	PMID:17332497
Molecular Function	GO:0017124	SH3 domain binding	CRB3	IPI	UniProtKB:Q5T2T1	Human	PMID:17332497
Cellular Component	GO:0045177	apical part of cell	Crb3	IDA		Mouse	PMID:24191021
Cellular Component	GO:0030054	cell junction	CRB3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	CRB3	HDA		Human	PMID:19056867
Cellular Component	GO:0032991	protein-containing complex	Crb3	IDA		Rat	PMID:18621709|RGD:5131983
Cellular Component	GO:0035003	subapical complex	Crb3	IDA		Mouse	PMID:16885194
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	crb3a	IMP	ZFIN:ZDB-MRPHLNO-060822-6	Zfish	PMID:16713951
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	crb3a	IMP	ZFIN:ZDB-MRPHLNO-060612-2	Zfish	PMID:16713951
Biological Process	GO:1901890	positive regulation of cell junction assembly	Crb3	IMP		Mouse	MGI:MGI:4939579|PMID:21145499
Biological Process	GO:0072659	protein localization to plasma membrane	CRB3	IDA		Human	PMID:17332497
Biological Process	GO:1902855	regulation of non-motile cilium assembly	crb3a	IMP	ZFIN:ZDB-GENO-180412-3	Zfish	PMID:28882989
Biological Process	GO:1902855	regulation of non-motile cilium assembly	crb3a	IMP	ZFIN:ZDB-GENO-180412-4	Zfish	PMID:28882989
Biological Process	GO:1902855	regulation of non-motile cilium assembly	crb3a	IGI	ZFIN:ZDB-GENO-180412-9	Zfish	PMID:28882989
Biological Process	GO:1902855	regulation of non-motile cilium assembly	crb3a	IGI	ZFIN:ZDB-GENO-180412-8	Zfish	PMID:28882989

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern