Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CPSF4
  • Mouse genes Cpsf4
  • Rat genes Cpsf4
  • Zfish genes cpsf4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cpsf4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CPSF4	IPI	UniProtKB:Q6P1J9	Human	PMID:19136632
Molecular Function	GO:0005515	protein binding	CPSF4	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CPSF4	IPI	UniProtKB:I6T1Z2	Human	PMID:28169297
Molecular Function	GO:0005515	protein binding	CPSF4	IPI	UniProtKB:Q194T2	Human	PMID:28169297
Molecular Function	GO:0003723	RNA binding	CPSF4	HDA		Human	PMID:22681889
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	CPSF4	IDA		Human	PMID:28473536
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CPSF4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	CPSF4	IDA		Human	PMID:21102410
Cellular Component	GO:0005654	nucleoplasm	CPSF4	IDA		Human	GO_REF:0000052
Biological Process	GO:0042462	eye photoreceptor cell development	cpsf4	IMP	ZFIN:ZDB-GENO-040217-4	Zfish	PMID:15716491
Biological Process	GO:0042462	eye photoreceptor cell development	cpsf4	IMP	ZFIN:ZDB-GENO-980202-73	Zfish	PMID:15716491

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern