Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COP1
  • Mouse genes Cop1
  • Rat genes Cop1
  • Zfish genes cop1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cop1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	COP1	IPI	UniProtKB:Q7L5Y6	Human	PMID:14739464
Molecular Function	GO:0005515	protein binding	COP1	IPI	UniProtKB:Q13330	Human	PMID:19805145
Molecular Function	GO:0005515	protein binding	COP1	IPI	UniProtKB:P31947	Human	PMID:20843328
Molecular Function	GO:0005515	protein binding	COP1	IPI	UniProtKB:P50549	Human	PMID:21572435
Molecular Function	GO:0005515	protein binding	COP1	IPI	UniProtKB:P31947	Human	PMID:21625211
Molecular Function	GO:0005515	protein binding	COP1	IPI	UniProtKB:Q7L5N1	Human	PMID:21625211
Molecular Function	GO:0005515	protein binding	COP1	IPI	UniProtKB:P14921-1	Human	PMID:25117710
Molecular Function	GO:0005515	protein binding	COP1	IPI	UniProtKB:P15036	Human	PMID:25117710
Molecular Function	GO:0005515	protein binding	COP1	IPI	UniProtKB:P15036	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	Cop1	IPI	UniProtKB:Q3U182	Mouse	MGI:MGI:3761061|PMID:17805301
Molecular Function	GO:0005515	protein binding	Cop1	IPI	UniProtKB:Q8K4K2	Mouse	MGI:MGI:3630230|PMID:16794074
Molecular Function	GO:0061630	ubiquitin protein ligase activity	COP1	IMP		Human	PMID:19805145
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	COP1	IDA		Human	PMID:14739464
Cellular Component	GO:0000139	Golgi membrane	Cop1	IDA		Rat	PMID:15147909|RGD:2306211
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	COP1	IMP		Human	PMID:19805145
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	COP1	IMP		Human	PMID:14739464
Biological Process	GO:0010212	response to ionizing radiation	COP1	IDA		Human	PMID:19805145

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern