Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COL4A6
  • Mouse genes Col4a6
  • Rat genes Col4a6
  • Zfish genes col4a6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Col4a6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	Col4a6	IDA		Mouse	PMID:10965041
Molecular Function	GO:0030020	extracellular matrix structural constituent conferring tensile strength	COL4A6	HDA		Human	PMID:28344315
Molecular Function	GO:0005515	protein binding	COL4A6	IPI	UniProtKB:P05067	Human	PMID:32814053
Cellular Component	GO:0005604	basement membrane	Col4a6	IDA		Mouse	PMID:18757743
Cellular Component	GO:0005604	basement membrane	Col4a6	IDA		Mouse	PMID:10534397
Cellular Component	GO:0005604	basement membrane	Col4a6	IDA		Mouse	PMID:19275937
Cellular Component	GO:0005604	basement membrane	Col4a6	IDA		Mouse	PMID:11732842
Cellular Component	GO:0005587	collagen type IV trimer	Col4a6	IDA		Mouse	PMID:12101409
Cellular Component	GO:0005587	collagen type IV trimer	Col4a6	IDA		Mouse	PMID:10965041
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A6	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A6	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL4A6	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col4a6	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col4a6	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Biological Process	GO:0048846	axon extension involved in axon guidance	col4a6	IMP	ZFIN:ZDB-GENO-090707-11	Zfish	PMID:26451951
Biological Process	GO:0071711	basement membrane organization	col4a6	IMP	ZFIN:ZDB-GENO-090707-11	Zfish	PMID:26451951
Biological Process	GO:0071230	cellular response to amino acid stimulus	Col4a6	IDA		Mouse	PMID:20548288
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Col4a6	IGI	MGI:MGI:88455	Mouse	PMID:10970885
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Col4a6	IGI	MGI:MGI:104688	Mouse	PMID:10970885
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Col4a6	IGI	MGI:MGI:88467	Mouse	PMID:10970885
Biological Process	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	Col4a6	IGI	MGI:MGI:88456	Mouse	PMID:10970885
Biological Process	GO:0030198	extracellular matrix organization	Col4a6	IDA		Mouse	PMID:10965041

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern